Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts
Pneumocystis jirovecii is a fungus that can cause life-threatening pneumonia in immunocompromised patients. Here, the authors sequence the genomes of P. jirovecii and two other Pneumocystisspecies, and show the unexpected absence of chitin (a near universal fungal cell wall component).
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Nature Portfolio
2016
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oai:doaj.org-article:a63cc72f702b47298d73bf4e878df92d2021-12-02T16:57:18ZGenome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts10.1038/ncomms107402041-1723https://doaj.org/article/a63cc72f702b47298d73bf4e878df92d2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10740https://doaj.org/toc/2041-1723Pneumocystis jirovecii is a fungus that can cause life-threatening pneumonia in immunocompromised patients. Here, the authors sequence the genomes of P. jirovecii and two other Pneumocystisspecies, and show the unexpected absence of chitin (a near universal fungal cell wall component).Liang MaZehua ChenDa Wei HuangGeetha KuttyMayumi IshiharaHonghui WangAmr AbouelleilLisa BishopEmma DaveyRebecca DengXilong DengLin FanGiovanna FantoniMichael FitzgeraldEmile GogineniJonathan M. GoldbergGrace HandleyXiaojun HuCharles HuberXiaoli JiaoKristine JonesJoshua Z. LevinYueqin LiuPendexter MacdonaldAlexandre MelnikovCastle RaleyMonica SassiBrad T. ShermanXiaohong SongSean SykesBao TranLaura WalshYun XiaJun YangSarah YoungQiandong ZengXin ZhengRobert StephensChad NusbaumBruce W. BirrenParastoo AzadiRichard A. LempickiChristina A. CuomoJoseph A. KovacsNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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DOAJ |
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DOAJ |
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EN |
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Science Q Liang Ma Zehua Chen Da Wei Huang Geetha Kutty Mayumi Ishihara Honghui Wang Amr Abouelleil Lisa Bishop Emma Davey Rebecca Deng Xilong Deng Lin Fan Giovanna Fantoni Michael Fitzgerald Emile Gogineni Jonathan M. Goldberg Grace Handley Xiaojun Hu Charles Huber Xiaoli Jiao Kristine Jones Joshua Z. Levin Yueqin Liu Pendexter Macdonald Alexandre Melnikov Castle Raley Monica Sassi Brad T. Sherman Xiaohong Song Sean Sykes Bao Tran Laura Walsh Yun Xia Jun Yang Sarah Young Qiandong Zeng Xin Zheng Robert Stephens Chad Nusbaum Bruce W. Birren Parastoo Azadi Richard A. Lempicki Christina A. Cuomo Joseph A. Kovacs Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| description |
Pneumocystis jirovecii is a fungus that can cause life-threatening pneumonia in immunocompromised patients. Here, the authors sequence the genomes of P. jirovecii and two other Pneumocystisspecies, and show the unexpected absence of chitin (a near universal fungal cell wall component). |
| format |
article |
| author |
Liang Ma Zehua Chen Da Wei Huang Geetha Kutty Mayumi Ishihara Honghui Wang Amr Abouelleil Lisa Bishop Emma Davey Rebecca Deng Xilong Deng Lin Fan Giovanna Fantoni Michael Fitzgerald Emile Gogineni Jonathan M. Goldberg Grace Handley Xiaojun Hu Charles Huber Xiaoli Jiao Kristine Jones Joshua Z. Levin Yueqin Liu Pendexter Macdonald Alexandre Melnikov Castle Raley Monica Sassi Brad T. Sherman Xiaohong Song Sean Sykes Bao Tran Laura Walsh Yun Xia Jun Yang Sarah Young Qiandong Zeng Xin Zheng Robert Stephens Chad Nusbaum Bruce W. Birren Parastoo Azadi Richard A. Lempicki Christina A. Cuomo Joseph A. Kovacs |
| author_facet |
Liang Ma Zehua Chen Da Wei Huang Geetha Kutty Mayumi Ishihara Honghui Wang Amr Abouelleil Lisa Bishop Emma Davey Rebecca Deng Xilong Deng Lin Fan Giovanna Fantoni Michael Fitzgerald Emile Gogineni Jonathan M. Goldberg Grace Handley Xiaojun Hu Charles Huber Xiaoli Jiao Kristine Jones Joshua Z. Levin Yueqin Liu Pendexter Macdonald Alexandre Melnikov Castle Raley Monica Sassi Brad T. Sherman Xiaohong Song Sean Sykes Bao Tran Laura Walsh Yun Xia Jun Yang Sarah Young Qiandong Zeng Xin Zheng Robert Stephens Chad Nusbaum Bruce W. Birren Parastoo Azadi Richard A. Lempicki Christina A. Cuomo Joseph A. Kovacs |
| author_sort |
Liang Ma |
| title |
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| title_short |
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| title_full |
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| title_fullStr |
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| title_full_unstemmed |
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| title_sort |
genome analysis of three pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/a63cc72f702b47298d73bf4e878df92d |
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