Cell-fate transition and determination analysis of mouse male germ cells throughout development
The full-term developmental profile of male germ cells remains undefined. Here, the authors use single-cell sequencing to investigate the transcriptome landscapes of mouse male germ cells throughout development and find several critical regulators for prenatal cell-fate determination.
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Nature Portfolio
2021
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oai:doaj.org-article:a64005ac6c2348c19b9171c05c36885e2021-11-28T12:31:58ZCell-fate transition and determination analysis of mouse male germ cells throughout development10.1038/s41467-021-27172-02041-1723https://doaj.org/article/a64005ac6c2348c19b9171c05c36885e2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27172-0https://doaj.org/toc/2041-1723The full-term developmental profile of male germ cells remains undefined. Here, the authors use single-cell sequencing to investigate the transcriptome landscapes of mouse male germ cells throughout development and find several critical regulators for prenatal cell-fate determination.Jiexiang ZhaoPing LuCong WanYaping HuangManman CuiXinyan YangYuqiong HuYi ZhengJi DongMei WangShu ZhangZhaoting LiuShuhui BianXiaoman WangRui WangShaofang RenDazhuang WangZhaokai YaoGang ChangFuchou TangXiao-Yang ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jiexiang Zhao Ping Lu Cong Wan Yaping Huang Manman Cui Xinyan Yang Yuqiong Hu Yi Zheng Ji Dong Mei Wang Shu Zhang Zhaoting Liu Shuhui Bian Xiaoman Wang Rui Wang Shaofang Ren Dazhuang Wang Zhaokai Yao Gang Chang Fuchou Tang Xiao-Yang Zhao Cell-fate transition and determination analysis of mouse male germ cells throughout development |
| description |
The full-term developmental profile of male germ cells remains undefined. Here, the authors use single-cell sequencing to investigate the transcriptome landscapes of mouse male germ cells throughout development and find several critical regulators for prenatal cell-fate determination. |
| format |
article |
| author |
Jiexiang Zhao Ping Lu Cong Wan Yaping Huang Manman Cui Xinyan Yang Yuqiong Hu Yi Zheng Ji Dong Mei Wang Shu Zhang Zhaoting Liu Shuhui Bian Xiaoman Wang Rui Wang Shaofang Ren Dazhuang Wang Zhaokai Yao Gang Chang Fuchou Tang Xiao-Yang Zhao |
| author_facet |
Jiexiang Zhao Ping Lu Cong Wan Yaping Huang Manman Cui Xinyan Yang Yuqiong Hu Yi Zheng Ji Dong Mei Wang Shu Zhang Zhaoting Liu Shuhui Bian Xiaoman Wang Rui Wang Shaofang Ren Dazhuang Wang Zhaokai Yao Gang Chang Fuchou Tang Xiao-Yang Zhao |
| author_sort |
Jiexiang Zhao |
| title |
Cell-fate transition and determination analysis of mouse male germ cells throughout development |
| title_short |
Cell-fate transition and determination analysis of mouse male germ cells throughout development |
| title_full |
Cell-fate transition and determination analysis of mouse male germ cells throughout development |
| title_fullStr |
Cell-fate transition and determination analysis of mouse male germ cells throughout development |
| title_full_unstemmed |
Cell-fate transition and determination analysis of mouse male germ cells throughout development |
| title_sort |
cell-fate transition and determination analysis of mouse male germ cells throughout development |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/a64005ac6c2348c19b9171c05c36885e |
| work_keys_str_mv |
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1718407910369787904 |