Depression and chronic pain in the elderly: links and management challenges

Panagiotis Zis,1 Argyro Daskalaki,2 Ilia Bountouni,3 Panagiota Sykioti,3 Giustino Varrassi,4 Antonella Paladini5 1Academic Department of Neurosciences, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; 2Department of Neurology, Evangelismos General Hospital, Athens, Greece; 3Belgrave...

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Autores principales:	Zis P, Daskalaki A, Bountouni I, Sykioti P, Varrassi G, Paladini A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	depression chronic pain elderly neuroinflammation Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/a64760239ffd4b39b5f94c6534c4324f
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spelling	oai:doaj.org-article:a64760239ffd4b39b5f94c6534c4324f2021-12-02T00:38:00ZDepression and chronic pain in the elderly: links and management challenges1178-1998https://doaj.org/article/a64760239ffd4b39b5f94c6534c4324f2017-04-01T00:00:00Zhttps://www.dovepress.com/depression-and-chronic-pain-in-the-elderly-links-and-management-challe-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Panagiotis Zis,1 Argyro Daskalaki,2 Ilia Bountouni,3 Panagiota Sykioti,3 Giustino Varrassi,4 Antonella Paladini5 1Academic Department of Neurosciences, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; 2Department of Neurology, Evangelismos General Hospital, Athens, Greece; 3Belgrave Liaison Team, Child and Adolescent Mental Health Services, South London and Maudsley NHS Foundation Trust, London, UK; 4Fondazione Paolo Procacci and European League against Pain, Rome, 5Department of MESVA, University of L’Aquila, L’Aquila, ItalyAbstract: Aging is an inevitable process and represents the accumulation of bodily alterations over time. Depression and chronic pain are highly prevalent in elderly populations. It is estimated that 13% of the elderly population will suffer simultaneously from the two conditions. Accumulating evidence suggests than neuroinflammation plays a critical role in the pathogenesis of both depression and chronic pain. Apart from the common pathophysiological mechanisms, however, the two entities have several clinical links. Their management is challenging for the pain physician; however, both pharmacologic and nonpharmacologic approaches are available and can be used when the two conditions are comorbid in the elderly patients.Keywords: depression, chronic pain, elderly, neuroinflammation, cognitive impairment, painZis PDaskalaki ABountouni ISykioti PVarrassi GPaladini ADove Medical Pressarticledepressionchronic painelderlyneuroinflammationGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 709-720 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	depression chronic pain elderly neuroinflammation Geriatrics RC952-954.6
spellingShingle	depression chronic pain elderly neuroinflammation Geriatrics RC952-954.6 Zis P Daskalaki A Bountouni I Sykioti P Varrassi G Paladini A Depression and chronic pain in the elderly: links and management challenges
description	Panagiotis Zis,1 Argyro Daskalaki,2 Ilia Bountouni,3 Panagiota Sykioti,3 Giustino Varrassi,4 Antonella Paladini5 1Academic Department of Neurosciences, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; 2Department of Neurology, Evangelismos General Hospital, Athens, Greece; 3Belgrave Liaison Team, Child and Adolescent Mental Health Services, South London and Maudsley NHS Foundation Trust, London, UK; 4Fondazione Paolo Procacci and European League against Pain, Rome, 5Department of MESVA, University of L’Aquila, L’Aquila, ItalyAbstract: Aging is an inevitable process and represents the accumulation of bodily alterations over time. Depression and chronic pain are highly prevalent in elderly populations. It is estimated that 13% of the elderly population will suffer simultaneously from the two conditions. Accumulating evidence suggests than neuroinflammation plays a critical role in the pathogenesis of both depression and chronic pain. Apart from the common pathophysiological mechanisms, however, the two entities have several clinical links. Their management is challenging for the pain physician; however, both pharmacologic and nonpharmacologic approaches are available and can be used when the two conditions are comorbid in the elderly patients.Keywords: depression, chronic pain, elderly, neuroinflammation, cognitive impairment, pain
format	article
author	Zis P Daskalaki A Bountouni I Sykioti P Varrassi G Paladini A
author_facet	Zis P Daskalaki A Bountouni I Sykioti P Varrassi G Paladini A
author_sort	Zis P
title	Depression and chronic pain in the elderly: links and management challenges
title_short	Depression and chronic pain in the elderly: links and management challenges
title_full	Depression and chronic pain in the elderly: links and management challenges
title_fullStr	Depression and chronic pain in the elderly: links and management challenges
title_full_unstemmed	Depression and chronic pain in the elderly: links and management challenges
title_sort	depression and chronic pain in the elderly: links and management challenges
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/a64760239ffd4b39b5f94c6534c4324f
work_keys_str_mv	AT zisp depressionandchronicpainintheelderlylinksandmanagementchallenges AT daskalakia depressionandchronicpainintheelderlylinksandmanagementchallenges AT bountounii depressionandchronicpainintheelderlylinksandmanagementchallenges AT sykiotip depressionandchronicpainintheelderlylinksandmanagementchallenges AT varrassig depressionandchronicpainintheelderlylinksandmanagementchallenges AT paladinia depressionandchronicpainintheelderlylinksandmanagementchallenges
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Depression and chronic pain in the elderly: links and management challenges

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