An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)

Abstract A simple modified sensor was developed with nicotinic acid hydrazide anchored on graphene oxide (NAHGO), by ultrasonic-assisted chemical route, using hydroxy benzotriazole as a mediator. Structural and morphologies of NAHGO samples were investigated in detail by Fourier-Transform Infrared s...

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Autores principales: Jemini Jose, Viswanathan Subramanian, Sadasivan Shaji, P. B. Sreeja
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Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:a64feb0b2f3d4d88809174442a92f23a2021-12-02T18:25:05ZAn electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)10.1038/s41598-021-89427-62045-2322https://doaj.org/article/a64feb0b2f3d4d88809174442a92f23a2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89427-6https://doaj.org/toc/2045-2322Abstract A simple modified sensor was developed with nicotinic acid hydrazide anchored on graphene oxide (NAHGO), by ultrasonic-assisted chemical route, using hydroxy benzotriazole as a mediator. Structural and morphologies of NAHGO samples were investigated in detail by Fourier-Transform Infrared spectroscopy (FT-IR), Powder X-ray diffraction (P-XRD), Raman spectroscopy, Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and Thermogravimetric analysis (TGA). The detailed morphological examination and electrochemical studies revealed the delaminated sheet with the tube-like structure of NAHGO provided the route for more electroactive surface which influenced the electrooxidation of caffeine with increased current. The electrochemical behaviour of NAHGO on a glassy carbon electrode (GCE) for caffeine detection was demonstrated by employing voltammetric techniques. The influence of scan rate, pH, and concentration on caffeine's peak current was also studied. The NAHGO sensor was employed for the determination of caffeine in imol plus and energy drinks. The detection limit determined was 8.7 × 10–9 M, and the best value was reported so far. The results show that NAHGO modified electrodes are one of the best preferences to establish new, efficient, and reliable analytical tools for the detection of caffeine.Jemini JoseViswanathan SubramanianSadasivan ShajiP. B. SreejaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Jemini Jose
Viswanathan Subramanian
Sadasivan Shaji
P. B. Sreeja
An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)
description Abstract A simple modified sensor was developed with nicotinic acid hydrazide anchored on graphene oxide (NAHGO), by ultrasonic-assisted chemical route, using hydroxy benzotriazole as a mediator. Structural and morphologies of NAHGO samples were investigated in detail by Fourier-Transform Infrared spectroscopy (FT-IR), Powder X-ray diffraction (P-XRD), Raman spectroscopy, Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and Thermogravimetric analysis (TGA). The detailed morphological examination and electrochemical studies revealed the delaminated sheet with the tube-like structure of NAHGO provided the route for more electroactive surface which influenced the electrooxidation of caffeine with increased current. The electrochemical behaviour of NAHGO on a glassy carbon electrode (GCE) for caffeine detection was demonstrated by employing voltammetric techniques. The influence of scan rate, pH, and concentration on caffeine's peak current was also studied. The NAHGO sensor was employed for the determination of caffeine in imol plus and energy drinks. The detection limit determined was 8.7 × 10–9 M, and the best value was reported so far. The results show that NAHGO modified electrodes are one of the best preferences to establish new, efficient, and reliable analytical tools for the detection of caffeine.
format article
author Jemini Jose
Viswanathan Subramanian
Sadasivan Shaji
P. B. Sreeja
author_facet Jemini Jose
Viswanathan Subramanian
Sadasivan Shaji
P. B. Sreeja
author_sort Jemini Jose
title An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)
title_short An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)
title_full An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)
title_fullStr An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)
title_full_unstemmed An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO)
title_sort electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (nahgo)
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a64feb0b2f3d4d88809174442a92f23a
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