Epidemiology of visceral leishmaniasis in Algeria: an update.

Visceral leishmaniasis (VL), a zoonotic disease caused by Leishmania infantum, is endemic in Algeria. This report describes a retrospective epidemiological study conducted on human VL to document the epidemiological profile at national level. All human VL cases notified by the National Institute of...

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Autores principales:	Amel Adel, Amel Boughoufalah, Claude Saegerman, Redgi De Deken, Zahida Bouchene, Abdelkrim Soukehal, Dirk Berkvens, Marleen Boelaert
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a659b6977bba45c7b0ff01240c3fab00
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spelling	oai:doaj.org-article:a659b6977bba45c7b0ff01240c3fab002021-11-18T08:14:50ZEpidemiology of visceral leishmaniasis in Algeria: an update.1932-620310.1371/journal.pone.0099207https://doaj.org/article/a659b6977bba45c7b0ff01240c3fab002014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24949958/?tool=EBIhttps://doaj.org/toc/1932-6203Visceral leishmaniasis (VL), a zoonotic disease caused by Leishmania infantum, is endemic in Algeria. This report describes a retrospective epidemiological study conducted on human VL to document the epidemiological profile at national level. All human VL cases notified by the National Institute of Public Health between 1998 and 2008 were investigated. In parallel all VL cases admitted to the university hospitals of Algiers were surveyed to estimate the underreporting ratio. Fifteen hundred and sixty-two human VL cases were reported in Algeria between 1998-2008 with an average annual reported incidence rate of 0.45 cases per 100,000 inhabitants, of which 81.42% were in the age range of 0-4 years. Cases were detected year-round, with a peak notification in May and June. One hundred and seventy patients were admitted to the university hospitals in Algiers in the same period, of which less than one in ten had been officially notified. Splenomegaly, fever, pallor and pancytopenia were the main clinical and laboratory features. Meglumine antimoniate was the first-line therapy for paediatric VL whereas the conventional amphotericin B was used for adult patients. Visceral leishmaniasis in Algeria shows the epidemiological profile of a paediatric disease with a decrease of the annual reported incidence rate. However, vigilance is required because of huge underreporting and an apparent propagation towards the south.Amel AdelAmel BoughoufalahClaude SaegermanRedgi De DekenZahida BoucheneAbdelkrim SoukehalDirk BerkvensMarleen BoelaertPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 6, p e99207 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Amel Adel Amel Boughoufalah Claude Saegerman Redgi De Deken Zahida Bouchene Abdelkrim Soukehal Dirk Berkvens Marleen Boelaert Epidemiology of visceral leishmaniasis in Algeria: an update.
description	Visceral leishmaniasis (VL), a zoonotic disease caused by Leishmania infantum, is endemic in Algeria. This report describes a retrospective epidemiological study conducted on human VL to document the epidemiological profile at national level. All human VL cases notified by the National Institute of Public Health between 1998 and 2008 were investigated. In parallel all VL cases admitted to the university hospitals of Algiers were surveyed to estimate the underreporting ratio. Fifteen hundred and sixty-two human VL cases were reported in Algeria between 1998-2008 with an average annual reported incidence rate of 0.45 cases per 100,000 inhabitants, of which 81.42% were in the age range of 0-4 years. Cases were detected year-round, with a peak notification in May and June. One hundred and seventy patients were admitted to the university hospitals in Algiers in the same period, of which less than one in ten had been officially notified. Splenomegaly, fever, pallor and pancytopenia were the main clinical and laboratory features. Meglumine antimoniate was the first-line therapy for paediatric VL whereas the conventional amphotericin B was used for adult patients. Visceral leishmaniasis in Algeria shows the epidemiological profile of a paediatric disease with a decrease of the annual reported incidence rate. However, vigilance is required because of huge underreporting and an apparent propagation towards the south.
format	article
author	Amel Adel Amel Boughoufalah Claude Saegerman Redgi De Deken Zahida Bouchene Abdelkrim Soukehal Dirk Berkvens Marleen Boelaert
author_facet	Amel Adel Amel Boughoufalah Claude Saegerman Redgi De Deken Zahida Bouchene Abdelkrim Soukehal Dirk Berkvens Marleen Boelaert
author_sort	Amel Adel
title	Epidemiology of visceral leishmaniasis in Algeria: an update.
title_short	Epidemiology of visceral leishmaniasis in Algeria: an update.
title_full	Epidemiology of visceral leishmaniasis in Algeria: an update.
title_fullStr	Epidemiology of visceral leishmaniasis in Algeria: an update.
title_full_unstemmed	Epidemiology of visceral leishmaniasis in Algeria: an update.
title_sort	epidemiology of visceral leishmaniasis in algeria: an update.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/a659b6977bba45c7b0ff01240c3fab00
work_keys_str_mv	AT ameladel epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT amelboughoufalah epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT claudesaegerman epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT redgidedeken epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT zahidabouchene epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT abdelkrimsoukehal epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT dirkberkvens epidemiologyofvisceralleishmaniasisinalgeriaanupdate AT marleenboelaert epidemiologyofvisceralleishmaniasisinalgeriaanupdate
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Epidemiology of visceral leishmaniasis in Algeria: an update.

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