Emergence of recombinant Mayaro virus strains from the Amazon basin

Abstract Mayaro virus (MAYV), causative agent of Mayaro Fever, is an arbovirus transmitted by Haemagogus mosquitoes. Despite recent attention due to the identification of several cases in South and Central America and the Caribbean, limited information on MAYV evolution and epidemiology exists and r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Carla Mavian, Brittany D. Rife, James Jarad Dollar, Eleonora Cella, Massimo Ciccozzi, Mattia C. F. Prosperi, John Lednicky, J. Glenn Morris, Ilaria Capua, Marco Salemi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a65ef62b08d04b47b45faf0c8dcb95e0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a65ef62b08d04b47b45faf0c8dcb95e0
record_format	dspace
spelling	oai:doaj.org-article:a65ef62b08d04b47b45faf0c8dcb95e02021-12-02T11:52:24ZEmergence of recombinant Mayaro virus strains from the Amazon basin10.1038/s41598-017-07152-52045-2322https://doaj.org/article/a65ef62b08d04b47b45faf0c8dcb95e02017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07152-5https://doaj.org/toc/2045-2322Abstract Mayaro virus (MAYV), causative agent of Mayaro Fever, is an arbovirus transmitted by Haemagogus mosquitoes. Despite recent attention due to the identification of several cases in South and Central America and the Caribbean, limited information on MAYV evolution and epidemiology exists and represents a barrier to prevention of further spread. We present a thorough spatiotemporal evolutionary study of MAYV full-genome sequences collected over the last sixty years within South America and Haiti, revealing recent recombination events and adaptation to a broad host and vector range, including Aedes mosquito species. We employed a Bayesian phylogeography approach to characterize the emergence of recombinants in Brazil and Haiti and report evidence in favor of the putative role of human mobility in facilitating recombination among MAYV strains from geographically distinct regions. Spatiotemporal characteristics of recombination events and the emergence of this previously neglected virus in Haiti, a known hub for pathogen spread to the Americas, warrants close monitoring of MAYV infection in the immediate future.Carla MavianBrittany D. RifeJames Jarad DollarEleonora CellaMassimo CiccozziMattia C. F. ProsperiJohn LednickyJ. Glenn MorrisIlaria CapuaMarco SalemiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Carla Mavian Brittany D. Rife James Jarad Dollar Eleonora Cella Massimo Ciccozzi Mattia C. F. Prosperi John Lednicky J. Glenn Morris Ilaria Capua Marco Salemi Emergence of recombinant Mayaro virus strains from the Amazon basin
description	Abstract Mayaro virus (MAYV), causative agent of Mayaro Fever, is an arbovirus transmitted by Haemagogus mosquitoes. Despite recent attention due to the identification of several cases in South and Central America and the Caribbean, limited information on MAYV evolution and epidemiology exists and represents a barrier to prevention of further spread. We present a thorough spatiotemporal evolutionary study of MAYV full-genome sequences collected over the last sixty years within South America and Haiti, revealing recent recombination events and adaptation to a broad host and vector range, including Aedes mosquito species. We employed a Bayesian phylogeography approach to characterize the emergence of recombinants in Brazil and Haiti and report evidence in favor of the putative role of human mobility in facilitating recombination among MAYV strains from geographically distinct regions. Spatiotemporal characteristics of recombination events and the emergence of this previously neglected virus in Haiti, a known hub for pathogen spread to the Americas, warrants close monitoring of MAYV infection in the immediate future.
format	article
author	Carla Mavian Brittany D. Rife James Jarad Dollar Eleonora Cella Massimo Ciccozzi Mattia C. F. Prosperi John Lednicky J. Glenn Morris Ilaria Capua Marco Salemi
author_facet	Carla Mavian Brittany D. Rife James Jarad Dollar Eleonora Cella Massimo Ciccozzi Mattia C. F. Prosperi John Lednicky J. Glenn Morris Ilaria Capua Marco Salemi
author_sort	Carla Mavian
title	Emergence of recombinant Mayaro virus strains from the Amazon basin
title_short	Emergence of recombinant Mayaro virus strains from the Amazon basin
title_full	Emergence of recombinant Mayaro virus strains from the Amazon basin
title_fullStr	Emergence of recombinant Mayaro virus strains from the Amazon basin
title_full_unstemmed	Emergence of recombinant Mayaro virus strains from the Amazon basin
title_sort	emergence of recombinant mayaro virus strains from the amazon basin
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a65ef62b08d04b47b45faf0c8dcb95e0
work_keys_str_mv	AT carlamavian emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT brittanydrife emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT jamesjaraddollar emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT eleonoracella emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT massimociccozzi emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT mattiacfprosperi emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT johnlednicky emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT jglennmorris emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT ilariacapua emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin AT marcosalemi emergenceofrecombinantmayarovirusstrainsfromtheamazonbasin
_version_	1718395061328150528

Emergence of recombinant Mayaro virus strains from the Amazon basin

Ejemplares similares