Dissecting myosin-5B mechanosensitivity and calcium regulation at the single molecule level

Myosin-5B is an actin-based motor important for endosome recycling, but the molecular mechanism underlying its motility remains unknown. Here authors use single molecule imaging and high-speed laser tweezers to dissect the mechanoenzymatic properties of myosin-5B, which shows processive motility wit...

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Autores principales: Lucia Gardini, Sarah M. Heissler, Claudia Arbore, Yi Yang, James R. Sellers, Francesco S. Pavone, Marco Capitanio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a663d8e49b69440c972ca488748037c2
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