Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity

Many transcription factors regulate gene expression in a lineage- and process-specific manner, despite being expressed in several cell types. Here, the authors show that the Hox transcription factor Ubx has lineage-specific interactomes, which contribute to its cell context-dependent functions.

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Autores principales:	Julie Carnesecchi, Gianluca Sigismondo, Katrin Domsch, Clara Eva Paula Baader, Mahmoud-Reza Rafiee, Jeroen Krijgsveld, Ingrid Lohmann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a6678fc5c7e94cb5a03caffaffaf36d4
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spelling	oai:doaj.org-article:a6678fc5c7e94cb5a03caffaffaf36d42021-12-02T14:40:28ZMulti-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity10.1038/s41467-020-15223-x2041-1723https://doaj.org/article/a6678fc5c7e94cb5a03caffaffaf36d42020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15223-xhttps://doaj.org/toc/2041-1723Many transcription factors regulate gene expression in a lineage- and process-specific manner, despite being expressed in several cell types. Here, the authors show that the Hox transcription factor Ubx has lineage-specific interactomes, which contribute to its cell context-dependent functions.Julie CarnesecchiGianluca SigismondoKatrin DomschClara Eva Paula BaaderMahmoud-Reza RafieeJeroen KrijgsveldIngrid LohmannNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julie Carnesecchi Gianluca Sigismondo Katrin Domsch Clara Eva Paula Baader Mahmoud-Reza Rafiee Jeroen Krijgsveld Ingrid Lohmann Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
description	Many transcription factors regulate gene expression in a lineage- and process-specific manner, despite being expressed in several cell types. Here, the authors show that the Hox transcription factor Ubx has lineage-specific interactomes, which contribute to its cell context-dependent functions.
format	article
author	Julie Carnesecchi Gianluca Sigismondo Katrin Domsch Clara Eva Paula Baader Mahmoud-Reza Rafiee Jeroen Krijgsveld Ingrid Lohmann
author_facet	Julie Carnesecchi Gianluca Sigismondo Katrin Domsch Clara Eva Paula Baader Mahmoud-Reza Rafiee Jeroen Krijgsveld Ingrid Lohmann
author_sort	Julie Carnesecchi
title	Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
title_short	Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
title_full	Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
title_fullStr	Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
title_full_unstemmed	Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
title_sort	multi-level and lineage-specific interactomes of the hox transcription factor ubx contribute to its functional specificity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a6678fc5c7e94cb5a03caffaffaf36d4
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Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity

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