Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.

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Detalles Bibliográficos
Autores principales: Yifei Miao, Nassim E. Ajami, Tse-Shun Huang, Feng-Mao Lin, Chih-Hong Lou, Yun-Ting Wang, Shuai Li, Jian Kang, Hannah Munkacsi, Mano R. Maurya, Shakti Gupta, Shu Chien, Shankar Subramaniam, Zhen Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a67095a0978f4a1bbc2ae67affad3970
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Descripción
Sumario:eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.