Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.

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Autores principales:	Yifei Miao, Nassim E. Ajami, Tse-Shun Huang, Feng-Mao Lin, Chih-Hong Lou, Yun-Ting Wang, Shuai Li, Jian Kang, Hannah Munkacsi, Mano R. Maurya, Shakti Gupta, Shu Chien, Shankar Subramaniam, Zhen Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a67095a0978f4a1bbc2ae67affad3970
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spelling	oai:doaj.org-article:a67095a0978f4a1bbc2ae67affad39702021-12-02T17:31:47ZEnhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function10.1038/s41467-017-02113-y2041-1723https://doaj.org/article/a67095a0978f4a1bbc2ae67affad39702018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02113-yhttps://doaj.org/toc/2041-1723eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.Yifei MiaoNassim E. AjamiTse-Shun HuangFeng-Mao LinChih-Hong LouYun-Ting WangShuai LiJian KangHannah MunkacsiMano R. MauryaShakti GuptaShu ChienShankar SubramaniamZhen ChenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yifei Miao Nassim E. Ajami Tse-Shun Huang Feng-Mao Lin Chih-Hong Lou Yun-Ting Wang Shuai Li Jian Kang Hannah Munkacsi Mano R. Maurya Shakti Gupta Shu Chien Shankar Subramaniam Zhen Chen Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
description	eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.
format	article
author	Yifei Miao Nassim E. Ajami Tse-Shun Huang Feng-Mao Lin Chih-Hong Lou Yun-Ting Wang Shuai Li Jian Kang Hannah Munkacsi Mano R. Maurya Shakti Gupta Shu Chien Shankar Subramaniam Zhen Chen
author_facet	Yifei Miao Nassim E. Ajami Tse-Shun Huang Feng-Mao Lin Chih-Hong Lou Yun-Ting Wang Shuai Li Jian Kang Hannah Munkacsi Mano R. Maurya Shakti Gupta Shu Chien Shankar Subramaniam Zhen Chen
author_sort	Yifei Miao
title	Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
title_short	Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
title_full	Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
title_fullStr	Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
title_full_unstemmed	Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
title_sort	enhancer-associated long non-coding rna leene regulates endothelial nitric oxide synthase and endothelial function
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a67095a0978f4a1bbc2ae67affad3970
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Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

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