Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface
ABSTRACT Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to in vivo signals is a promising new approach for the diagnosis, treatment, and prevention of disease. However, because the design of disease-responsive circuits is limited by a relatively small pool of k...
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Autores principales: | Alexander D. Naydich, Shannon N. Nangle, Johannes J. Bues, Disha Trivedi, Nabeel Nissar, Mara C. Inniss, Matthew J. Niederhuber, Jeffrey C. Way, Pamela A. Silver, David T. Riglar |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/a670a59b6f6541ef8395330c64f5fd82 |
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