Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors

Clathrin lattices coat flat membrane regions, called plaques, whose regulation and function are poorly understood. Here the authors find that plaques are regulated by actin dynamics and contain both the endocytic and the cell adhesion machineries, and are involved in endocytosis of specific cargos,...

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Autores principales:	Daniela Leyton-Puig, Tadamoto Isogai, Elisabetta Argenzio, Bram van den Broek, Jeffrey Klarenbeek, Hans Janssen, Kees Jalink, Metello Innocenti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a675eefc386747468d8c562060201f7b
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spelling	oai:doaj.org-article:a675eefc386747468d8c562060201f7b2021-12-02T14:42:01ZFlat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors10.1038/ncomms160682041-1723https://doaj.org/article/a675eefc386747468d8c562060201f7b2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16068https://doaj.org/toc/2041-1723Clathrin lattices coat flat membrane regions, called plaques, whose regulation and function are poorly understood. Here the authors find that plaques are regulated by actin dynamics and contain both the endocytic and the cell adhesion machineries, and are involved in endocytosis of specific cargos, and cell migration.Daniela Leyton-PuigTadamoto IsogaiElisabetta ArgenzioBram van den BroekJeffrey KlarenbeekHans JanssenKees JalinkMetello InnocentiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniela Leyton-Puig Tadamoto Isogai Elisabetta Argenzio Bram van den Broek Jeffrey Klarenbeek Hans Janssen Kees Jalink Metello Innocenti Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
description	Clathrin lattices coat flat membrane regions, called plaques, whose regulation and function are poorly understood. Here the authors find that plaques are regulated by actin dynamics and contain both the endocytic and the cell adhesion machineries, and are involved in endocytosis of specific cargos, and cell migration.
format	article
author	Daniela Leyton-Puig Tadamoto Isogai Elisabetta Argenzio Bram van den Broek Jeffrey Klarenbeek Hans Janssen Kees Jalink Metello Innocenti
author_facet	Daniela Leyton-Puig Tadamoto Isogai Elisabetta Argenzio Bram van den Broek Jeffrey Klarenbeek Hans Janssen Kees Jalink Metello Innocenti
author_sort	Daniela Leyton-Puig
title	Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
title_short	Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
title_full	Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
title_fullStr	Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
title_full_unstemmed	Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
title_sort	flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a675eefc386747468d8c562060201f7b
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Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors

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