Murine models of sickle cell disease and beta-thalassemia demonstrate pulmonary hypertension with distinctive features

Sickle cell anemia and β-thalassemia intermedia are very different genetically determined hemoglobinopathies predisposing to pulmonary hypertension. The etiologies responsible for the associated development of pulmonary hypertension in both diseases are multi-factorial with extensive mechanistic con...

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Auteurs principaux: Paul W. Buehler, Delaney Swindle, David I. Pak, Mehdi A. Fini, Kathryn Hassell, Rachelle Nuss, Rebecca B. Wilkerson, Angelo D’Alessandro, David C. Irwin
Format: article
Langue:EN
Publié: SAGE Publishing 2021
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Accès en ligne:https://doaj.org/article/a6772f4e041245f38a3c7f1237ddb78b
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