Iron induces two distinct Ca2+ signalling cascades in astrocytes

Wenzheng Guan and Maosheng Xia et al. use a combination of pharmacological, genetic, and calcium imaging approaches to describe two mechanisms of iron-induced astrocytic calcium signaling. Altogether, these results suggest that astrocytes may act as a barrier to excessive iron in the brain, thereby...

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Autores principales:	Wenzheng Guan, Maosheng Xia, Ming Ji, Beina Chen, Shuai Li, Manman Zhang, Shanshan Liang, Binjie Chen, Wenliang Gong, Chengyi Dong, Gehua Wen, Xiaoni Zhan, Dianjun Zhang, Xinyu Li, Yuefei Zhou, Dawei Guan, Alexei Verkhratsky, Baoman Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a67c1f1c03484bec8f4a7b5d8d413b09
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:a67c1f1c03484bec8f4a7b5d8d413b092021-12-02T14:29:14ZIron induces two distinct Ca2+ signalling cascades in astrocytes10.1038/s42003-021-02060-x2399-3642https://doaj.org/article/a67c1f1c03484bec8f4a7b5d8d413b092021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02060-xhttps://doaj.org/toc/2399-3642Wenzheng Guan and Maosheng Xia et al. use a combination of pharmacological, genetic, and calcium imaging approaches to describe two mechanisms of iron-induced astrocytic calcium signaling. Altogether, these results suggest that astrocytes may act as a barrier to excessive iron in the brain, thereby improving our understanding of the role of astrocytes in normal neurodevelopment.Wenzheng GuanMaosheng XiaMing JiBeina ChenShuai LiManman ZhangShanshan LiangBinjie ChenWenliang GongChengyi DongGehua WenXiaoni ZhanDianjun ZhangXinyu LiYuefei ZhouDawei GuanAlexei VerkhratskyBaoman LiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Wenzheng Guan Maosheng Xia Ming Ji Beina Chen Shuai Li Manman Zhang Shanshan Liang Binjie Chen Wenliang Gong Chengyi Dong Gehua Wen Xiaoni Zhan Dianjun Zhang Xinyu Li Yuefei Zhou Dawei Guan Alexei Verkhratsky Baoman Li Iron induces two distinct Ca2+ signalling cascades in astrocytes
description	Wenzheng Guan and Maosheng Xia et al. use a combination of pharmacological, genetic, and calcium imaging approaches to describe two mechanisms of iron-induced astrocytic calcium signaling. Altogether, these results suggest that astrocytes may act as a barrier to excessive iron in the brain, thereby improving our understanding of the role of astrocytes in normal neurodevelopment.
format	article
author	Wenzheng Guan Maosheng Xia Ming Ji Beina Chen Shuai Li Manman Zhang Shanshan Liang Binjie Chen Wenliang Gong Chengyi Dong Gehua Wen Xiaoni Zhan Dianjun Zhang Xinyu Li Yuefei Zhou Dawei Guan Alexei Verkhratsky Baoman Li
author_facet	Wenzheng Guan Maosheng Xia Ming Ji Beina Chen Shuai Li Manman Zhang Shanshan Liang Binjie Chen Wenliang Gong Chengyi Dong Gehua Wen Xiaoni Zhan Dianjun Zhang Xinyu Li Yuefei Zhou Dawei Guan Alexei Verkhratsky Baoman Li
author_sort	Wenzheng Guan
title	Iron induces two distinct Ca2+ signalling cascades in astrocytes
title_short	Iron induces two distinct Ca2+ signalling cascades in astrocytes
title_full	Iron induces two distinct Ca2+ signalling cascades in astrocytes
title_fullStr	Iron induces two distinct Ca2+ signalling cascades in astrocytes
title_full_unstemmed	Iron induces two distinct Ca2+ signalling cascades in astrocytes
title_sort	iron induces two distinct ca2+ signalling cascades in astrocytes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a67c1f1c03484bec8f4a7b5d8d413b09
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Iron induces two distinct Ca2+ signalling cascades in astrocytes

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