SODIUM POLYPRENYL PHOSPHATE (PHOSPRENYL) EXERTS AN IL-2-DEPENDENT RESTORATIVE EFFECT UPON IN VIVO DTH INHIBITION
Abstract. We have shown that polyprenyl phosphate (phosprenyl) competes with interleukin 2 for binding with serum γ-globulin. It was also demonstrated that phosprenyl restores delayed type hypersensitivity induced by Listeria monocytogenes, after its inhibition with a γ-globulin which binds to IL-2...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
SPb RAACI
2014
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/a67cad233db4442185b9784f6b3022fd |
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| Sumario: | Abstract. We have shown that polyprenyl phosphate (phosprenyl) competes with interleukin 2 for binding with serum γ-globulin. It was also demonstrated that phosprenyl restores delayed type hypersensitivity induced by Listeria monocytogenes, after its inhibition with a γ-globulin which binds to IL-2 and blocks its activity. A role of serum γ-globulin and Phosprenyl in regulation of IL-2-dependent processes is discussed. |
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