Interactions between prescription drugs in hospitalized geriatric patients

Background: It is estimated that, on average, a hospitalized patient receives between six and ten medications simultaneously. Moreover, older adults present physiological changes typical of aging, polypharmacy, and polypathology. The above considerably increases the possibility of drug interactions....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Erika Palacios-Rosas, Alejandra d. C. Castilla-Hernández
Formato:	article
Lenguaje:	EN ES
Publicado:	Permanyer 2021
Materias:	Medication errors. Geriatrics. Polypharmacy. Drug interactions. Drug prescriptions. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a67e60a011e84d0e87e91728d789bd49
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a67e60a011e84d0e87e91728d789bd49
record_format	dspace
spelling	oai:doaj.org-article:a67e60a011e84d0e87e91728d789bd492021-11-04T09:25:23ZInteractions between prescription drugs in hospitalized geriatric patients10.24875/RMU.210000211665-57962530-0709https://doaj.org/article/a67e60a011e84d0e87e91728d789bd492021-07-01T00:00:00Zhttps://www.medicinauniversitaria.org/frame_esp.php?id=139https://doaj.org/toc/1665-5796https://doaj.org/toc/2530-0709Background: It is estimated that, on average, a hospitalized patient receives between six and ten medications simultaneously. Moreover, older adults present physiological changes typical of aging, polypharmacy, and polypathology. The above considerably increases the possibility of drug interactions. Objective: Detect potential drug interactions (PDI) in 49 clinical files of hospitalized geriatric patients in Puebla, Mexico. Material and methods: The platform drugs.com was used to analyze forty-nine clinical charts of hospitalized geriatric patients 65 years or older. Results: 185 different types of PDI were detected, affecting 85.7% of the patients; 18.5% of these with high severity, 71% moderate, and 10.5% low. The most frequent PDI found on five occasions was Ondansetron-Tramadol, considered as serious. The most frequent drug involved was dexamethasone, repeating seventeen times, and causing nineteen PDIs. Conclusions: It is important to exercise pharmacovigilance in hospitalized geriatric patients to prevent the appearance of adverse reactions associated with drug interactions. Erika Palacios-RosasAlejandra d. C. Castilla-HernándezPermanyerarticleMedication errors. Geriatrics. Polypharmacy. Drug interactions. Drug prescriptions.Medicine (General)R5-920ENESMedicina Universitaria, Vol 23, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN ES
topic	Medication errors. Geriatrics. Polypharmacy. Drug interactions. Drug prescriptions. Medicine (General) R5-920
spellingShingle	Medication errors. Geriatrics. Polypharmacy. Drug interactions. Drug prescriptions. Medicine (General) R5-920 Erika Palacios-Rosas Alejandra d. C. Castilla-Hernández Interactions between prescription drugs in hospitalized geriatric patients
description	Background: It is estimated that, on average, a hospitalized patient receives between six and ten medications simultaneously. Moreover, older adults present physiological changes typical of aging, polypharmacy, and polypathology. The above considerably increases the possibility of drug interactions. Objective: Detect potential drug interactions (PDI) in 49 clinical files of hospitalized geriatric patients in Puebla, Mexico. Material and methods: The platform drugs.com was used to analyze forty-nine clinical charts of hospitalized geriatric patients 65 years or older. Results: 185 different types of PDI were detected, affecting 85.7% of the patients; 18.5% of these with high severity, 71% moderate, and 10.5% low. The most frequent PDI found on five occasions was Ondansetron-Tramadol, considered as serious. The most frequent drug involved was dexamethasone, repeating seventeen times, and causing nineteen PDIs. Conclusions: It is important to exercise pharmacovigilance in hospitalized geriatric patients to prevent the appearance of adverse reactions associated with drug interactions.
format	article
author	Erika Palacios-Rosas Alejandra d. C. Castilla-Hernández
author_facet	Erika Palacios-Rosas Alejandra d. C. Castilla-Hernández
author_sort	Erika Palacios-Rosas
title	Interactions between prescription drugs in hospitalized geriatric patients
title_short	Interactions between prescription drugs in hospitalized geriatric patients
title_full	Interactions between prescription drugs in hospitalized geriatric patients
title_fullStr	Interactions between prescription drugs in hospitalized geriatric patients
title_full_unstemmed	Interactions between prescription drugs in hospitalized geriatric patients
title_sort	interactions between prescription drugs in hospitalized geriatric patients
publisher	Permanyer
publishDate	2021
url	https://doaj.org/article/a67e60a011e84d0e87e91728d789bd49
work_keys_str_mv	AT erikapalaciosrosas interactionsbetweenprescriptiondrugsinhospitalizedgeriatricpatients AT alejandradccastillahernandez interactionsbetweenprescriptiondrugsinhospitalizedgeriatricpatients
_version_	1718444981492908032

Interactions between prescription drugs in hospitalized geriatric patients

Ejemplares similares