DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle

DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle

Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single molecules of DNA.

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Autores principales: Andrey Mikheikin, Anita Olsen, Kevin Leslie, Freddie Russell-Pavier, Andrew Yacoot, Loren Picco, Oliver Payton, Amir Toor, Alden Chesney, James K. Gimzewski, Bud Mishra, Jason Reed
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Q
Acceso en línea:https://doaj.org/article/a68808d05e344a9c825d7924d933f9bc
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spelling oai:doaj.org-article:a68808d05e344a9c825d7924d933f9bc2021-12-02T14:41:22ZDNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle10.1038/s41467-017-01891-92041-1723https://doaj.org/article/a68808d05e344a9c825d7924d933f9bc2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01891-9https://doaj.org/toc/2041-1723Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single molecules of DNA.Andrey MikheikinAnita OlsenKevin LeslieFreddie Russell-PavierAndrew YacootLoren PiccoOliver PaytonAmir ToorAlden ChesneyJames K. GimzewskiBud MishraJason ReedNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andrey Mikheikin
Anita Olsen
Kevin Leslie
Freddie Russell-Pavier
Andrew Yacoot
Loren Picco
Oliver Payton
Amir Toor
Alden Chesney
James K. Gimzewski
Bud Mishra
Jason Reed
DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
description Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single molecules of DNA.
format article
author Andrey Mikheikin
Anita Olsen
Kevin Leslie
Freddie Russell-Pavier
Andrew Yacoot
Loren Picco
Oliver Payton
Amir Toor
Alden Chesney
James K. Gimzewski
Bud Mishra
Jason Reed
author_facet Andrey Mikheikin
Anita Olsen
Kevin Leslie
Freddie Russell-Pavier
Andrew Yacoot
Loren Picco
Oliver Payton
Amir Toor
Alden Chesney
James K. Gimzewski
Bud Mishra
Jason Reed
author_sort Andrey Mikheikin
title DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
title_short DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
title_full DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
title_fullStr DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
title_full_unstemmed DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
title_sort dna nanomapping using crispr-cas9 as a programmable nanoparticle
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/a68808d05e344a9c825d7924d933f9bc
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