DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle

DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle

Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single molecules of DNA.

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Bibliographic Details
Main Authors: Andrey Mikheikin, Anita Olsen, Kevin Leslie, Freddie Russell-Pavier, Andrew Yacoot, Loren Picco, Oliver Payton, Amir Toor, Alden Chesney, James K. Gimzewski, Bud Mishra, Jason Reed
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
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Online Access:https://doaj.org/article/a68808d05e344a9c825d7924d933f9bc
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Internet

https://doaj.org/article/a68808d05e344a9c825d7924d933f9bc

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