TGF-β induces ST2 and programs ILC2 development

TGF-β induces ST2 and programs ILC2 development

TGF-β is thought to be important for group 2 innate lymphoid cell (ILC2) function. Here the authors show that TGF-β drives expression of ST2 specifically in ILC2 progenitors and thereby is also important for the development of ILC2s in the bone marrow.

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Autores principales: Li Wang, Jun Tang, Xia Yang, Peter Zanvit, Kairong Cui, Wai Lim Ku, Wenwen Jin, Dunfang Zhang, Nathan Goldberg, Alexander Cain, Bing Ni, Keji Zhao, Yuzhang Wu, WanJun Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/a688433a35754ccc8c3fb4caa9137c56
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spelling oai:doaj.org-article:a688433a35754ccc8c3fb4caa9137c562021-12-02T17:33:14ZTGF-β induces ST2 and programs ILC2 development10.1038/s41467-019-13734-w2041-1723https://doaj.org/article/a688433a35754ccc8c3fb4caa9137c562020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13734-whttps://doaj.org/toc/2041-1723TGF-β is thought to be important for group 2 innate lymphoid cell (ILC2) function. Here the authors show that TGF-β drives expression of ST2 specifically in ILC2 progenitors and thereby is also important for the development of ILC2s in the bone marrow.Li WangJun TangXia YangPeter ZanvitKairong CuiWai Lim KuWenwen JinDunfang ZhangNathan GoldbergAlexander CainBing NiKeji ZhaoYuzhang WuWanJun ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Li Wang
Jun Tang
Xia Yang
Peter Zanvit
Kairong Cui
Wai Lim Ku
Wenwen Jin
Dunfang Zhang
Nathan Goldberg
Alexander Cain
Bing Ni
Keji Zhao
Yuzhang Wu
WanJun Chen
TGF-β induces ST2 and programs ILC2 development
description TGF-β is thought to be important for group 2 innate lymphoid cell (ILC2) function. Here the authors show that TGF-β drives expression of ST2 specifically in ILC2 progenitors and thereby is also important for the development of ILC2s in the bone marrow.
format article
author Li Wang
Jun Tang
Xia Yang
Peter Zanvit
Kairong Cui
Wai Lim Ku
Wenwen Jin
Dunfang Zhang
Nathan Goldberg
Alexander Cain
Bing Ni
Keji Zhao
Yuzhang Wu
WanJun Chen
author_facet Li Wang
Jun Tang
Xia Yang
Peter Zanvit
Kairong Cui
Wai Lim Ku
Wenwen Jin
Dunfang Zhang
Nathan Goldberg
Alexander Cain
Bing Ni
Keji Zhao
Yuzhang Wu
WanJun Chen
author_sort Li Wang
title TGF-β induces ST2 and programs ILC2 development
title_short TGF-β induces ST2 and programs ILC2 development
title_full TGF-β induces ST2 and programs ILC2 development
title_fullStr TGF-β induces ST2 and programs ILC2 development
title_full_unstemmed TGF-β induces ST2 and programs ILC2 development
title_sort tgf-β induces st2 and programs ilc2 development
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a688433a35754ccc8c3fb4caa9137c56
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AT kairongcui tgfbinducesst2andprogramsilc2development
AT wailimku tgfbinducesst2andprogramsilc2development
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AT bingni tgfbinducesst2andprogramsilc2development
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