Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule

Untreatable bacterial infections are a critical public health care issue. In addition to increasing antibiotic resistance, bacteria that are in slow-growing or nongrowing states, or that live inside mammalian cells, are typically insensitive to clinical antibiotics and therefore difficult to eradic...

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Autores principales: Jamie L. Dombach, Joaquin L. J. Quintana, Corrella S. Detweiler
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/a68af8cbc9f5475c85a35b8a114d37ca
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spelling oai:doaj.org-article:a68af8cbc9f5475c85a35b8a114d37ca2021-11-03T21:52:35ZStaphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule2150-751110.1128/mBio.01801-21https://doaj.org/article/a68af8cbc9f5475c85a35b8a114d37ca2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01801-21https://doaj.org/toc/2150-7511 Untreatable bacterial infections are a critical public health care issue. In addition to increasing antibiotic resistance, bacteria that are in slow-growing or nongrowing states, or that live inside mammalian cells, are typically insensitive to clinical antibiotics and therefore difficult to eradicate.Jamie L. DombachJoaquin L. J. QuintanaCorrella S. DetweilerAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Jamie L. Dombach
Joaquin L. J. Quintana
Corrella S. Detweiler
Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule
description Untreatable bacterial infections are a critical public health care issue. In addition to increasing antibiotic resistance, bacteria that are in slow-growing or nongrowing states, or that live inside mammalian cells, are typically insensitive to clinical antibiotics and therefore difficult to eradicate.
format article
author Jamie L. Dombach
Joaquin L. J. Quintana
Corrella S. Detweiler
author_facet Jamie L. Dombach
Joaquin L. J. Quintana
Corrella S. Detweiler
author_sort Jamie L. Dombach
title Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule
title_short Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule
title_full Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule
title_fullStr Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule
title_full_unstemmed Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule
title_sort staphylococcal bacterial persister cells, biofilms, and intracellular infection are disrupted by jd1, a membrane-damaging small molecule
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/a68af8cbc9f5475c85a35b8a114d37ca
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AT correllasdetweiler staphylococcalbacterialpersistercellsbiofilmsandintracellularinfectionaredisruptedbyjd1amembranedamagingsmallmolecule
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