Age-seroprevalence curves for the multi-strain structure of influenza A virus

Multi-strain pathogens, such as influenza, present challenges for interpretation of seroprevalence data as estimates may vary by strain. Here, the authors develop a method for estimating age-specific seroprevalence based on principal components analysis and apply it to influenza data from Vietnam.

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Autores principales: Dao Nguyen Vinh, Nguyen Thi Duy Nhat, Erwin de Bruin, Nguyen Ha Thao Vy, Tran Thi Nhu Thao, Huynh Thi Phuong, Pham Hong Anh, Stacy Todd, Tran Minh Quan, Nguyen Thi Le Thanh, Nguyen Thi Nam Lien, Nguyen Thi Hong Ha, Tran Thi Kim Hong, Pham Quang Thai, Marc Choisy, Tran Dang Nguyen, Cameron P. Simmons, Guy E. Thwaites, Hannah E. Clapham, Nguyen Van Vinh Chau, Marion Koopmans, Maciej F. Boni
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a68e51831ae9495fbcae680c69278194
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spelling oai:doaj.org-article:a68e51831ae9495fbcae680c692781942021-11-21T12:36:21ZAge-seroprevalence curves for the multi-strain structure of influenza A virus10.1038/s41467-021-26948-82041-1723https://doaj.org/article/a68e51831ae9495fbcae680c692781942021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26948-8https://doaj.org/toc/2041-1723Multi-strain pathogens, such as influenza, present challenges for interpretation of seroprevalence data as estimates may vary by strain. Here, the authors develop a method for estimating age-specific seroprevalence based on principal components analysis and apply it to influenza data from Vietnam.Dao Nguyen VinhNguyen Thi Duy NhatErwin de BruinNguyen Ha Thao VyTran Thi Nhu ThaoHuynh Thi PhuongPham Hong AnhStacy ToddTran Minh QuanNguyen Thi Le ThanhNguyen Thi Nam LienNguyen Thi Hong HaTran Thi Kim HongPham Quang ThaiMarc ChoisyTran Dang NguyenCameron P. SimmonsGuy E. ThwaitesHannah E. ClaphamNguyen Van Vinh ChauMarion KoopmansMaciej F. BoniNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dao Nguyen Vinh
Nguyen Thi Duy Nhat
Erwin de Bruin
Nguyen Ha Thao Vy
Tran Thi Nhu Thao
Huynh Thi Phuong
Pham Hong Anh
Stacy Todd
Tran Minh Quan
Nguyen Thi Le Thanh
Nguyen Thi Nam Lien
Nguyen Thi Hong Ha
Tran Thi Kim Hong
Pham Quang Thai
Marc Choisy
Tran Dang Nguyen
Cameron P. Simmons
Guy E. Thwaites
Hannah E. Clapham
Nguyen Van Vinh Chau
Marion Koopmans
Maciej F. Boni
Age-seroprevalence curves for the multi-strain structure of influenza A virus
description Multi-strain pathogens, such as influenza, present challenges for interpretation of seroprevalence data as estimates may vary by strain. Here, the authors develop a method for estimating age-specific seroprevalence based on principal components analysis and apply it to influenza data from Vietnam.
format article
author Dao Nguyen Vinh
Nguyen Thi Duy Nhat
Erwin de Bruin
Nguyen Ha Thao Vy
Tran Thi Nhu Thao
Huynh Thi Phuong
Pham Hong Anh
Stacy Todd
Tran Minh Quan
Nguyen Thi Le Thanh
Nguyen Thi Nam Lien
Nguyen Thi Hong Ha
Tran Thi Kim Hong
Pham Quang Thai
Marc Choisy
Tran Dang Nguyen
Cameron P. Simmons
Guy E. Thwaites
Hannah E. Clapham
Nguyen Van Vinh Chau
Marion Koopmans
Maciej F. Boni
author_facet Dao Nguyen Vinh
Nguyen Thi Duy Nhat
Erwin de Bruin
Nguyen Ha Thao Vy
Tran Thi Nhu Thao
Huynh Thi Phuong
Pham Hong Anh
Stacy Todd
Tran Minh Quan
Nguyen Thi Le Thanh
Nguyen Thi Nam Lien
Nguyen Thi Hong Ha
Tran Thi Kim Hong
Pham Quang Thai
Marc Choisy
Tran Dang Nguyen
Cameron P. Simmons
Guy E. Thwaites
Hannah E. Clapham
Nguyen Van Vinh Chau
Marion Koopmans
Maciej F. Boni
author_sort Dao Nguyen Vinh
title Age-seroprevalence curves for the multi-strain structure of influenza A virus
title_short Age-seroprevalence curves for the multi-strain structure of influenza A virus
title_full Age-seroprevalence curves for the multi-strain structure of influenza A virus
title_fullStr Age-seroprevalence curves for the multi-strain structure of influenza A virus
title_full_unstemmed Age-seroprevalence curves for the multi-strain structure of influenza A virus
title_sort age-seroprevalence curves for the multi-strain structure of influenza a virus
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a68e51831ae9495fbcae680c69278194
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