Degradation of complex arabinoxylans by human colonic Bacteroidetes

Human gut bacteria can degrade arabinoxylans, polysaccharides found in dietary fiber. Here, Pereira et al. identify a bacterial gene cluster encoding esterases for degradation of complex arabinoxylans. The action of these enzymes results in accumulation of ferulic acid, a phenolic compound with anti...

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Autores principales: Gabriel V. Pereira, Ahmed M. Abdel-Hamid, Soumajit Dutta, Corina N. D’Alessandro-Gabazza, Daniel Wefers, Jacob A. Farris, Shiv Bajaj, Zdzislaw Wawrzak, Haruyuki Atomi, Roderick I. Mackie, Esteban C. Gabazza, Diwakar Shukla, Nicole M. Koropatkin, Isaac Cann
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a693c91c120a47879d9d18e9d9404ea3
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spelling oai:doaj.org-article:a693c91c120a47879d9d18e9d9404ea32021-12-02T13:56:46ZDegradation of complex arabinoxylans by human colonic Bacteroidetes10.1038/s41467-020-20737-52041-1723https://doaj.org/article/a693c91c120a47879d9d18e9d9404ea32021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20737-5https://doaj.org/toc/2041-1723Human gut bacteria can degrade arabinoxylans, polysaccharides found in dietary fiber. Here, Pereira et al. identify a bacterial gene cluster encoding esterases for degradation of complex arabinoxylans. The action of these enzymes results in accumulation of ferulic acid, a phenolic compound with antioxidative and immunomodulatory properties.Gabriel V. PereiraAhmed M. Abdel-HamidSoumajit DuttaCorina N. D’Alessandro-GabazzaDaniel WefersJacob A. FarrisShiv BajajZdzislaw WawrzakHaruyuki AtomiRoderick I. MackieEsteban C. GabazzaDiwakar ShuklaNicole M. KoropatkinIsaac CannNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gabriel V. Pereira
Ahmed M. Abdel-Hamid
Soumajit Dutta
Corina N. D’Alessandro-Gabazza
Daniel Wefers
Jacob A. Farris
Shiv Bajaj
Zdzislaw Wawrzak
Haruyuki Atomi
Roderick I. Mackie
Esteban C. Gabazza
Diwakar Shukla
Nicole M. Koropatkin
Isaac Cann
Degradation of complex arabinoxylans by human colonic Bacteroidetes
description Human gut bacteria can degrade arabinoxylans, polysaccharides found in dietary fiber. Here, Pereira et al. identify a bacterial gene cluster encoding esterases for degradation of complex arabinoxylans. The action of these enzymes results in accumulation of ferulic acid, a phenolic compound with antioxidative and immunomodulatory properties.
format article
author Gabriel V. Pereira
Ahmed M. Abdel-Hamid
Soumajit Dutta
Corina N. D’Alessandro-Gabazza
Daniel Wefers
Jacob A. Farris
Shiv Bajaj
Zdzislaw Wawrzak
Haruyuki Atomi
Roderick I. Mackie
Esteban C. Gabazza
Diwakar Shukla
Nicole M. Koropatkin
Isaac Cann
author_facet Gabriel V. Pereira
Ahmed M. Abdel-Hamid
Soumajit Dutta
Corina N. D’Alessandro-Gabazza
Daniel Wefers
Jacob A. Farris
Shiv Bajaj
Zdzislaw Wawrzak
Haruyuki Atomi
Roderick I. Mackie
Esteban C. Gabazza
Diwakar Shukla
Nicole M. Koropatkin
Isaac Cann
author_sort Gabriel V. Pereira
title Degradation of complex arabinoxylans by human colonic Bacteroidetes
title_short Degradation of complex arabinoxylans by human colonic Bacteroidetes
title_full Degradation of complex arabinoxylans by human colonic Bacteroidetes
title_fullStr Degradation of complex arabinoxylans by human colonic Bacteroidetes
title_full_unstemmed Degradation of complex arabinoxylans by human colonic Bacteroidetes
title_sort degradation of complex arabinoxylans by human colonic bacteroidetes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a693c91c120a47879d9d18e9d9404ea3
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