New synthetic thrombin inhibitors: molecular design and experimental verification.

New synthetic thrombin inhibitors: molecular design and experimental verification.

<h4>Background</h4>The development of new anticoagulants is an important goal for the improvement of thromboses treatments.<h4>Objectives</h4>The design, synthesis and experimental testing of new safe and effective small molecule direct thrombin inhibitors for intravenous adm...

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Autores principales: Elena I Sinauridze, Alexey N Romanov, Irina V Gribkova, Olga A Kondakova, Stepan S Surov, Aleksander S Gorbatenko, Andrey A Butylin, Mikhail Yu Monakov, Alexey A Bogolyubov, Yuryi V Kuznetsov, Vladimir B Sulimov, Fazoyl I Ataullakhanov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a69be1a33b304dbd8675b481fc9eaf89
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