The anesthetic sevoflurane induces tau trafficking from neurons to microglia

Using their previously developed nanobeam-sensor technology to detect tau protein in the blood, Yuanlin Dong et al. find that the anaesthetic sevoflurane induces trafficking of tau from neurons to microglia in mice. They further see that microglia can take up tau, leading to Il-6 production, overall...

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Autores principales:	Yuanlin Dong, Feng Liang, Lining Huang, Fang Fang, Guang Yang, Rudolph E. Tanzi, Yiying Zhang, Qimin Quan, Zhongcong Xie
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a69fd188a3b14fd7bc38a56ea8d1fec1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:a69fd188a3b14fd7bc38a56ea8d1fec12021-12-02T15:55:21ZThe anesthetic sevoflurane induces tau trafficking from neurons to microglia10.1038/s42003-021-02047-82399-3642https://doaj.org/article/a69fd188a3b14fd7bc38a56ea8d1fec12021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02047-8https://doaj.org/toc/2399-3642Using their previously developed nanobeam-sensor technology to detect tau protein in the blood, Yuanlin Dong et al. find that the anaesthetic sevoflurane induces trafficking of tau from neurons to microglia in mice. They further see that microglia can take up tau, leading to Il-6 production, overall bringing new insights into the mechanism of sevoflurane-mediated cognitive impairment.Yuanlin DongFeng LiangLining HuangFang FangGuang YangRudolph E. TanziYiying ZhangQimin QuanZhongcong XieNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Yuanlin Dong Feng Liang Lining Huang Fang Fang Guang Yang Rudolph E. Tanzi Yiying Zhang Qimin Quan Zhongcong Xie The anesthetic sevoflurane induces tau trafficking from neurons to microglia
description	Using their previously developed nanobeam-sensor technology to detect tau protein in the blood, Yuanlin Dong et al. find that the anaesthetic sevoflurane induces trafficking of tau from neurons to microglia in mice. They further see that microglia can take up tau, leading to Il-6 production, overall bringing new insights into the mechanism of sevoflurane-mediated cognitive impairment.
format	article
author	Yuanlin Dong Feng Liang Lining Huang Fang Fang Guang Yang Rudolph E. Tanzi Yiying Zhang Qimin Quan Zhongcong Xie
author_facet	Yuanlin Dong Feng Liang Lining Huang Fang Fang Guang Yang Rudolph E. Tanzi Yiying Zhang Qimin Quan Zhongcong Xie
author_sort	Yuanlin Dong
title	The anesthetic sevoflurane induces tau trafficking from neurons to microglia
title_short	The anesthetic sevoflurane induces tau trafficking from neurons to microglia
title_full	The anesthetic sevoflurane induces tau trafficking from neurons to microglia
title_fullStr	The anesthetic sevoflurane induces tau trafficking from neurons to microglia
title_full_unstemmed	The anesthetic sevoflurane induces tau trafficking from neurons to microglia
title_sort	anesthetic sevoflurane induces tau trafficking from neurons to microglia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a69fd188a3b14fd7bc38a56ea8d1fec1
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The anesthetic sevoflurane induces tau trafficking from neurons to microglia

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