The anesthetic sevoflurane induces tau trafficking from neurons to microglia
Using their previously developed nanobeam-sensor technology to detect tau protein in the blood, Yuanlin Dong et al. find that the anaesthetic sevoflurane induces trafficking of tau from neurons to microglia in mice. They further see that microglia can take up tau, leading to Il-6 production, overall...
Saved in:
Main Authors: | Yuanlin Dong, Feng Liang, Lining Huang, Fang Fang, Guang Yang, Rudolph E. Tanzi, Yiying Zhang, Qimin Quan, Zhongcong Xie |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/a69fd188a3b14fd7bc38a56ea8d1fec1 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
MAC-Sparing Effect of Transdermal Fentanyl in Sevoflurane-Anesthetized Sheep
by: Lauren Duffee, et al.
Published: (2018) -
The effects of the general anesthetic sevoflurane on neurotransmission: an experimental and computational study
by: Jonathan Mapelli, et al.
Published: (2021) -
Peripheral surgical wounding and age-dependent neuroinflammation in mice.
by: Zhipeng Xu, et al.
Published: (2014) -
Comparison of sevoflurane and desflurane on effect-site concentration of remifentanil for preventing anesthetic emergence cough in elderly female patients undergoing laparoscopic cholecystectomy
by: Kim HY, et al.
Published: (2018) -
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia
by: Alessio Colombo, et al.
Published: (2021)