The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination.

The heterodimeric Ku complex has been shown to participate in DNA repair and telomere regulation in a variety of organisms. Here we report a detailed characterization of the function of Ku70 in the diploid fungal pathogen Candida albicans. Both ku70 heterozygous and homozygous deletion mutants have...

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Auteurs principaux: Lidia Chico, Toni Ciudad, Min Hsu, Neal F Lue, Germán Larriba
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/a6a023e3682d4b13a61607351dc3c509
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