RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER

Uterine cervical cancer is among the main items of modern oncology. Determination of SCCA levels in blood serum of women with locally disseminated forms of uterine cervical cancer has a great significance for estimation the extent of lesions, tumor progression patterns, as well as treatment monitori...

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Autores principales:	I. L. Baturina, I. Yu. Orner, O. S. Abramovskikh, L. F. Telesheva, A. V, Zharov, K. V. Nikushkina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	scc tcell immunity cervical cancer Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/a6b868196a97417698c84131266ccac4
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spelling	oai:doaj.org-article:a6b868196a97417698c84131266ccac42021-11-18T08:03:38ZRELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER1563-06252313-741X10.15789/1563-0625-2010-4-5-387-392https://doaj.org/article/a6b868196a97417698c84131266ccac42014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/209https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XUterine cervical cancer is among the main items of modern oncology. Determination of SCCA levels in blood serum of women with locally disseminated forms of uterine cervical cancer has a great significance for estimation the extent of lesions, tumor progression patterns, as well as treatment monitoring. During our study, we have determined that, before starting a specific treatment, all the patients with locally disseminated forms of cervical cancer had high serum levels of SCCA, along with suppressed anti-tumor immunity.Interestingly, high SCCA levels in blood serum proved to correlate with a decrease in anti-tumor immunity factors in those patients who showed a negative dynamics of tumor progression within one year after the therapy was performed. Meanwhile, the patients with positive post-treatment dynamics exhibited a significant decrease of SCCA levels over a year after therapy, as compared with appropriate pre-treatment values, accompanied by increase in anti-tumor immunity markers in these cases.I. L. BaturinaI. Yu. OrnerO. S. AbramovskikhL. F. TeleshevaA. V, ZharovK. V. NikushkinaSPb RAACIarticlescctcell immunitycervical cancerImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 4-5, Pp 387-392 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	scc tcell immunity cervical cancer Immunologic diseases. Allergy RC581-607
spellingShingle	scc tcell immunity cervical cancer Immunologic diseases. Allergy RC581-607 I. L. Baturina I. Yu. Orner O. S. Abramovskikh L. F. Telesheva A. V, Zharov K. V. Nikushkina RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER
description	Uterine cervical cancer is among the main items of modern oncology. Determination of SCCA levels in blood serum of women with locally disseminated forms of uterine cervical cancer has a great significance for estimation the extent of lesions, tumor progression patterns, as well as treatment monitoring. During our study, we have determined that, before starting a specific treatment, all the patients with locally disseminated forms of cervical cancer had high serum levels of SCCA, along with suppressed anti-tumor immunity.Interestingly, high SCCA levels in blood serum proved to correlate with a decrease in anti-tumor immunity factors in those patients who showed a negative dynamics of tumor progression within one year after the therapy was performed. Meanwhile, the patients with positive post-treatment dynamics exhibited a significant decrease of SCCA levels over a year after therapy, as compared with appropriate pre-treatment values, accompanied by increase in anti-tumor immunity markers in these cases.
format	article
author	I. L. Baturina I. Yu. Orner O. S. Abramovskikh L. F. Telesheva A. V, Zharov K. V. Nikushkina
author_facet	I. L. Baturina I. Yu. Orner O. S. Abramovskikh L. F. Telesheva A. V, Zharov K. V. Nikushkina
author_sort	I. L. Baturina
title	RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER
title_short	RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER
title_full	RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER
title_fullStr	RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER
title_full_unstemmed	RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER
title_sort	relationship between t cell immunity parameters and smooth-cell carcinoma antigen (scca) contents in blood serum from the patients with local disseminated forms of uterine cervix cancer
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/a6b868196a97417698c84131266ccac4
work_keys_str_mv	AT ilbaturina relationshipbetweentcellimmunityparametersandsmoothcellcarcinomaantigensccacontentsinbloodserumfromthepatientswithlocaldisseminatedformsofuterinecervixcancer AT iyuorner relationshipbetweentcellimmunityparametersandsmoothcellcarcinomaantigensccacontentsinbloodserumfromthepatientswithlocaldisseminatedformsofuterinecervixcancer AT osabramovskikh relationshipbetweentcellimmunityparametersandsmoothcellcarcinomaantigensccacontentsinbloodserumfromthepatientswithlocaldisseminatedformsofuterinecervixcancer AT lftelesheva relationshipbetweentcellimmunityparametersandsmoothcellcarcinomaantigensccacontentsinbloodserumfromthepatientswithlocaldisseminatedformsofuterinecervixcancer AT avzharov relationshipbetweentcellimmunityparametersandsmoothcellcarcinomaantigensccacontentsinbloodserumfromthepatientswithlocaldisseminatedformsofuterinecervixcancer AT kvnikushkina relationshipbetweentcellimmunityparametersandsmoothcellcarcinomaantigensccacontentsinbloodserumfromthepatientswithlocaldisseminatedformsofuterinecervixcancer
_version_	1718422561415495680

RELATIONSHIP BETWEEN T CELL IMMUNITY PARAMETERS AND SMOOTH-CELL CARCINOMA ANTIGEN (SCCA) CONTENTS IN BLOOD SERUM FROM THE PATIENTS WITH LOCAL DISSEMINATED FORMS OF UTERINE CERVIX CANCER

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