Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis

Abstract For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrum...

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Auteurs principaux: Masanori Ikeda, Kozo Tanaka
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Q
Accès en ligne:https://doaj.org/article/a6bc99e2b9d1486c985b8a8f2a6afb60
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