The Making and Breaking of Serine-ADP-Ribosylation in the DNA Damage Response
ADP-ribosylation is a widespread posttranslational modification that is of particular therapeutic relevance due to its involvement in DNA repair. In response to DNA damage, PARP1 and 2 are the main enzymes that catalyze ADP-ribosylation at damage sites. Recently, serine was identified as the primary...
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Main Authors: | , , |
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Format: | article |
Language: | EN |
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Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/a6c0b2c3e77d4bb3a4984da97dafc795 |
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