Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitation of InsP and PP-InsP isomers in cells and tissue...

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Autores principales:	Danye Qiu, Miranda S. Wilson, Verena B. Eisenbeis, Robert K. Harmel, Esther Riemer, Thomas M. Haas, Christopher Wittwer, Nikolaus Jork, Chunfang Gu, Stephen B. Shears, Gabriel Schaaf, Bernd Kammerer, Dorothea Fiedler, Adolfo Saiardi, Henning J. Jessen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a6c9f68025794db3aaf128b31c15130b
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spelling	oai:doaj.org-article:a6c9f68025794db3aaf128b31c15130b2021-12-02T14:42:47ZAnalysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry10.1038/s41467-020-19928-x2041-1723https://doaj.org/article/a6c9f68025794db3aaf128b31c15130b2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19928-xhttps://doaj.org/toc/2041-1723Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitation of InsP and PP-InsP isomers in cells and tissues.Danye QiuMiranda S. WilsonVerena B. EisenbeisRobert K. HarmelEsther RiemerThomas M. HaasChristopher WittwerNikolaus JorkChunfang GuStephen B. ShearsGabriel SchaafBernd KammererDorothea FiedlerAdolfo SaiardiHenning J. JessenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Danye Qiu Miranda S. Wilson Verena B. Eisenbeis Robert K. Harmel Esther Riemer Thomas M. Haas Christopher Wittwer Nikolaus Jork Chunfang Gu Stephen B. Shears Gabriel Schaaf Bernd Kammerer Dorothea Fiedler Adolfo Saiardi Henning J. Jessen Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
description	Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitation of InsP and PP-InsP isomers in cells and tissues.
format	article
author	Danye Qiu Miranda S. Wilson Verena B. Eisenbeis Robert K. Harmel Esther Riemer Thomas M. Haas Christopher Wittwer Nikolaus Jork Chunfang Gu Stephen B. Shears Gabriel Schaaf Bernd Kammerer Dorothea Fiedler Adolfo Saiardi Henning J. Jessen
author_facet	Danye Qiu Miranda S. Wilson Verena B. Eisenbeis Robert K. Harmel Esther Riemer Thomas M. Haas Christopher Wittwer Nikolaus Jork Chunfang Gu Stephen B. Shears Gabriel Schaaf Bernd Kammerer Dorothea Fiedler Adolfo Saiardi Henning J. Jessen
author_sort	Danye Qiu
title	Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
title_short	Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
title_full	Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
title_fullStr	Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
title_full_unstemmed	Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
title_sort	analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a6c9f68025794db3aaf128b31c15130b
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Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

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