MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance
Abstract Chemoresistance constitutes a major challenge in the treatment of triple-negative breast cancer (TNBC). Mixed-Lineage Kinase 4 (MLK4) is frequently amplified or overexpressed in TNBC where it facilitates the aggressive growth and migratory potential of breast cancer cells. However, the func...
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Autores principales: | , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Publishing Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a6cbcdae3c1744a89c3691e28b0246d5 |
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