Ultrasonic microbubble VEGF gene delivery improves angiogenesis of senescent endothelial progenitor cells

Ultrasonic microbubble VEGF gene delivery improves angiogenesis of senescent endothelial progenitor cells

Abstract The therapeutic effects of ultrasonic microbubble transfection (UMT)-based vascular endothelial growth factor 165 (VEGF165) gene delivery on young and senescent endothelial progenitor cells (EPCs) were investigated. By UMT, plasmid DNA (pDNA) can be delivered into both young EPCs and senesc...

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Autores principales: Yi-Nan Lee, Yih-Jer Wu, Hsin-I. Lee, Hsueh-Hsiao Wang, Chiung-Yin Chang, Ting-Yi Tien, Chao-Feng Lin, Cheng-Huang Su, Hung-I. Yeh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/a6debfccfd0d48b29733ab2468255380
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