Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 3...

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Autores principales: Arvind Gharbharan, Carlijn C. E. Jordans, Corine GeurtsvanKessel, Jan G. den Hollander, Faiz Karim, Femke P. N. Mollema, Janneke E. Stalenhoef – Schukken, Anthonius Dofferhoff, Inge Ludwig, Adrianus Koster, Robert-Jan Hassing, Jeannet C. Bos, Geert R. van Pottelberge, Imro N. Vlasveld, Heidi S. M. Ammerlaan, Elena M. van Leeuwen – Segarceanu, Jelle Miedema, Menno van der Eerden, Thijs J. Schrama, Grigorios Papageorgiou, Peter te Boekhorst, Francis H. Swaneveld, Yvonne M. Mueller, Marco W. J. Schreurs, Jeroen J. A. van Kampen, Barry Rockx, Nisreen M. A. Okba, Peter D. Katsikis, Marion P. G. Koopmans, Bart L. Haagmans, Casper Rokx, Bart J. A. Rijnders
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Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:a6dfe323ebd74308ad646da02ba72d202021-12-02T15:49:27ZEffects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection10.1038/s41467-021-23469-22041-1723https://doaj.org/article/a6dfe323ebd74308ad646da02ba72d202021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23469-2https://doaj.org/toc/2041-1723There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 300 mL convalescent plasma.Arvind GharbharanCarlijn C. E. JordansCorine GeurtsvanKesselJan G. den HollanderFaiz KarimFemke P. N. MollemaJanneke E. Stalenhoef – SchukkenAnthonius DofferhoffInge LudwigAdrianus KosterRobert-Jan HassingJeannet C. BosGeert R. van PottelbergeImro N. VlasveldHeidi S. M. AmmerlaanElena M. van Leeuwen – SegarceanuJelle MiedemaMenno van der EerdenThijs J. SchramaGrigorios PapageorgiouPeter te BoekhorstFrancis H. SwaneveldYvonne M. MuellerMarco W. J. SchreursJeroen J. A. van KampenBarry RockxNisreen M. A. OkbaPeter D. KatsikisMarion P. G. KoopmansBart L. HaagmansCasper RokxBart J. A. RijndersNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Arvind Gharbharan
Carlijn C. E. Jordans
Corine GeurtsvanKessel
Jan G. den Hollander
Faiz Karim
Femke P. N. Mollema
Janneke E. Stalenhoef – Schukken
Anthonius Dofferhoff
Inge Ludwig
Adrianus Koster
Robert-Jan Hassing
Jeannet C. Bos
Geert R. van Pottelberge
Imro N. Vlasveld
Heidi S. M. Ammerlaan
Elena M. van Leeuwen – Segarceanu
Jelle Miedema
Menno van der Eerden
Thijs J. Schrama
Grigorios Papageorgiou
Peter te Boekhorst
Francis H. Swaneveld
Yvonne M. Mueller
Marco W. J. Schreurs
Jeroen J. A. van Kampen
Barry Rockx
Nisreen M. A. Okba
Peter D. Katsikis
Marion P. G. Koopmans
Bart L. Haagmans
Casper Rokx
Bart J. A. Rijnders
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
description There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 300 mL convalescent plasma.
format article
author Arvind Gharbharan
Carlijn C. E. Jordans
Corine GeurtsvanKessel
Jan G. den Hollander
Faiz Karim
Femke P. N. Mollema
Janneke E. Stalenhoef – Schukken
Anthonius Dofferhoff
Inge Ludwig
Adrianus Koster
Robert-Jan Hassing
Jeannet C. Bos
Geert R. van Pottelberge
Imro N. Vlasveld
Heidi S. M. Ammerlaan
Elena M. van Leeuwen – Segarceanu
Jelle Miedema
Menno van der Eerden
Thijs J. Schrama
Grigorios Papageorgiou
Peter te Boekhorst
Francis H. Swaneveld
Yvonne M. Mueller
Marco W. J. Schreurs
Jeroen J. A. van Kampen
Barry Rockx
Nisreen M. A. Okba
Peter D. Katsikis
Marion P. G. Koopmans
Bart L. Haagmans
Casper Rokx
Bart J. A. Rijnders
author_facet Arvind Gharbharan
Carlijn C. E. Jordans
Corine GeurtsvanKessel
Jan G. den Hollander
Faiz Karim
Femke P. N. Mollema
Janneke E. Stalenhoef – Schukken
Anthonius Dofferhoff
Inge Ludwig
Adrianus Koster
Robert-Jan Hassing
Jeannet C. Bos
Geert R. van Pottelberge
Imro N. Vlasveld
Heidi S. M. Ammerlaan
Elena M. van Leeuwen – Segarceanu
Jelle Miedema
Menno van der Eerden
Thijs J. Schrama
Grigorios Papageorgiou
Peter te Boekhorst
Francis H. Swaneveld
Yvonne M. Mueller
Marco W. J. Schreurs
Jeroen J. A. van Kampen
Barry Rockx
Nisreen M. A. Okba
Peter D. Katsikis
Marion P. G. Koopmans
Bart L. Haagmans
Casper Rokx
Bart J. A. Rijnders
author_sort Arvind Gharbharan
title Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
title_short Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
title_full Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
title_fullStr Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
title_full_unstemmed Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
title_sort effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe sars-cov-2 infection
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a6dfe323ebd74308ad646da02ba72d20
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