Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)

A review of studies on the comparison of the effectiveness of surgical treatment of malignant trophoblastic tumors before the start of standard chemotherapy and in terms of combination treatment is presented. According to Russian and foreign studies, surgical treatment is relevant for patients with...

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Autores principales:	Aleksandr F. Maslennikov, Liudmila A. Meshcheriakova, Viktor V. Kuznetsov, Vladimir P. Kozachenko, Igor G. Komarov
Formato:	article
Lenguaje:	RU
Publicado:	IP Habib O.N. 2020
Materias:	trophoblastic tumor surgical treatment of trophoblastic tumors trophoblastic disease hydatidiform mole Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/a6dff2097eed45e3843b15129e52e727
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spelling	oai:doaj.org-article:a6dff2097eed45e3843b15129e52e7272021-11-30T17:03:34ZSurgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)1815-14341815-144210.26442/18151434.2020.1.200036https://doaj.org/article/a6dff2097eed45e3843b15129e52e7272020-05-01T00:00:00Zhttps://modernonco.orscience.ru/1815-1434/article/viewFile/34169/22582https://doaj.org/toc/1815-1434https://doaj.org/toc/1815-1442A review of studies on the comparison of the effectiveness of surgical treatment of malignant trophoblastic tumors before the start of standard chemotherapy and in terms of combination treatment is presented. According to Russian and foreign studies, surgical treatment is relevant for patients with primary or metastatic tumor resistance. The article presents the results of treatment of patients after various types of operations. The most common volume of surgery was a hysterectomy. The article also discusses the results of treatment of benign forms of trophoblastic disease. Surgical treatment of a malignant trophoblastic tumor before the start of standard chemotherapy was performed according to vital indications or in connection with a tumor determined by imaging methods. And the analysis carried out in Blokhin National Medical Research Center of Oncology showed expected prognoses for patients who underwent surgical treatment prior to the start of standard chemotherapy regimens. Such patients were admitted to the clinic with a resistant or disseminated form of the tumor. During their treatment, high-dose chemotherapy or additional surgical interventions were required, which significantly worsened the prognosis of the disease. In the opposite case, when removing a localized resistant primary tumor or its metastasis, in the postoperative period, chemotherapy was not carried out in connection with marker remission.Aleksandr F. MaslennikovLiudmila A. MeshcheriakovaViktor V. KuznetsovVladimir P. KozachenkoIgor G. KomarovIP Habib O.N.articletrophoblastic tumorsurgical treatment of trophoblastic tumorstrophoblastic diseasehydatidiform moleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282RUСовременная онкология, Vol 22, Iss 1, Pp 34-39 (2020)
institution	DOAJ
collection	DOAJ
language	RU
topic	trophoblastic tumor surgical treatment of trophoblastic tumors trophoblastic disease hydatidiform mole Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	trophoblastic tumor surgical treatment of trophoblastic tumors trophoblastic disease hydatidiform mole Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Aleksandr F. Maslennikov Liudmila A. Meshcheriakova Viktor V. Kuznetsov Vladimir P. Kozachenko Igor G. Komarov Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)
description	A review of studies on the comparison of the effectiveness of surgical treatment of malignant trophoblastic tumors before the start of standard chemotherapy and in terms of combination treatment is presented. According to Russian and foreign studies, surgical treatment is relevant for patients with primary or metastatic tumor resistance. The article presents the results of treatment of patients after various types of operations. The most common volume of surgery was a hysterectomy. The article also discusses the results of treatment of benign forms of trophoblastic disease. Surgical treatment of a malignant trophoblastic tumor before the start of standard chemotherapy was performed according to vital indications or in connection with a tumor determined by imaging methods. And the analysis carried out in Blokhin National Medical Research Center of Oncology showed expected prognoses for patients who underwent surgical treatment prior to the start of standard chemotherapy regimens. Such patients were admitted to the clinic with a resistant or disseminated form of the tumor. During their treatment, high-dose chemotherapy or additional surgical interventions were required, which significantly worsened the prognosis of the disease. In the opposite case, when removing a localized resistant primary tumor or its metastasis, in the postoperative period, chemotherapy was not carried out in connection with marker remission.
format	article
author	Aleksandr F. Maslennikov Liudmila A. Meshcheriakova Viktor V. Kuznetsov Vladimir P. Kozachenko Igor G. Komarov
author_facet	Aleksandr F. Maslennikov Liudmila A. Meshcheriakova Viktor V. Kuznetsov Vladimir P. Kozachenko Igor G. Komarov
author_sort	Aleksandr F. Maslennikov
title	Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)
title_short	Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)
title_full	Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)
title_fullStr	Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)
title_full_unstemmed	Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)
title_sort	surgical treatment of trophoblastic disease. modern concept and contradictions (literature review)
publisher	IP Habib O.N.
publishDate	2020
url	https://doaj.org/article/a6dff2097eed45e3843b15129e52e727
work_keys_str_mv	AT aleksandrfmaslennikov surgicaltreatmentoftrophoblasticdiseasemodernconceptandcontradictionsliteraturereview AT liudmilaameshcheriakova surgicaltreatmentoftrophoblasticdiseasemodernconceptandcontradictionsliteraturereview AT viktorvkuznetsov surgicaltreatmentoftrophoblasticdiseasemodernconceptandcontradictionsliteraturereview AT vladimirpkozachenko surgicaltreatmentoftrophoblasticdiseasemodernconceptandcontradictionsliteraturereview AT igorgkomarov surgicaltreatmentoftrophoblasticdiseasemodernconceptandcontradictionsliteraturereview
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Surgical treatment of trophoblastic disease. Modern concept and contradictions (literature review)

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