Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation
Ming-Kung Wu,1 Li-Wen Hsu,2 Kuang-Tzu Huang,3 Chih-Che Lin,2 Chih-Chi Wang,2 Ting-Lung Lin,2 Wei-Feng Li,2 Shigeru Goto,2 Chao-Long Chen,2 Chien-Chih Chen1 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Liver Tran...
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Dove Medical Press
2018
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oai:doaj.org-article:a6e2ed92cfdd452e80c2c4e2725014902021-12-02T08:31:59ZAssessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation1178-2021https://doaj.org/article/a6e2ed92cfdd452e80c2c4e2725014902018-08-01T00:00:00Zhttps://www.dovepress.com/assessment-of-relevant-factors-with-respect-to-psychosocial-properties-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Ming-Kung Wu,1 Li-Wen Hsu,2 Kuang-Tzu Huang,3 Chih-Che Lin,2 Chih-Chi Wang,2 Ting-Lung Lin,2 Wei-Feng Li,2 Shigeru Goto,2 Chao-Long Chen,2 Chien-Chih Chen1 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 3Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan Background: Living donor liver transplantation (LDLT) has been developed as one of gold standard treatments for end-stage liver disease. Mental health is a required selection criterion for adult living liver donors and may influence the quality of life after operation. Patients and methods: A total of 1,210 potential living donor candidates for liver transplantation (LT) underwent psychosocial evaluation that included a semi-structured interview, multi-choice self-reported inventory (Beck Depression Inventory-2nd edition [BDI-II], Beck Anxiety Inventory [BAI]), and the family APGAR (Adaptability, Partnership, Growth, Affection, Resolve) index. The test results were compared by family relationships, and subgroups were classified based on the donation type: 1) parents to children, 2) grown children to parents, 3) siblings to siblings, 4) spouses to spouses, and 5) other relatives to other relatives. Results: The BDI-II (P < 0.001) and BAI differed considerably according to the donation type in potential donor candidates. Compared with other subgroups, parents donating to their children suffered the most severe psychological stress before LDLT and exhibited more depressive (P < 0.001) and anxiety symptoms. However, the stress associated with grown children donating to their parents, siblings, and spouses was not significantly higher than it was for other relatives. Furthermore, a significant negative correlation existed between family APGAR scores and the severity of depression and anxiety (P < 0.001) among potential donor candidates. Conclusion: These results indicate the importance of understanding potential donor candidates’ psychological characteristics before LT. Greater anxiety and depression may be exhibited by parent donors due to the distress from fears of death or illness of the recipients, or their guilty feeling for their child. Additionally, family dysfunction also revealed more depression and anxiety. Such donor candidates should be given more extensive pre-donation counseling for minimizing pre-LDLT psychological stress. Keywords: living donor candidates, psychosocial evaluation, depression, anxiety, family function, family relationshipWu MKHsu LWHuang KTLin CCWang CCLin TLLi WFGoto SChen CLChen CCDove Medical PressarticleLiving donor candidatespsychosocial evaluationdepressionanxietyfamily functionfamily relationshipNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 1999-2005 (2018) |
| institution |
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| collection |
DOAJ |
| language |
EN |
| topic |
Living donor candidates psychosocial evaluation depression anxiety family function family relationship Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Living donor candidates psychosocial evaluation depression anxiety family function family relationship Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Wu MK Hsu LW Huang KT Lin CC Wang CC Lin TL Li WF Goto S Chen CL Chen CC Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| description |
Ming-Kung Wu,1 Li-Wen Hsu,2 Kuang-Tzu Huang,3 Chih-Che Lin,2 Chih-Chi Wang,2 Ting-Lung Lin,2 Wei-Feng Li,2 Shigeru Goto,2 Chao-Long Chen,2 Chien-Chih Chen1 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 3Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan Background: Living donor liver transplantation (LDLT) has been developed as one of gold standard treatments for end-stage liver disease. Mental health is a required selection criterion for adult living liver donors and may influence the quality of life after operation. Patients and methods: A total of 1,210 potential living donor candidates for liver transplantation (LT) underwent psychosocial evaluation that included a semi-structured interview, multi-choice self-reported inventory (Beck Depression Inventory-2nd edition [BDI-II], Beck Anxiety Inventory [BAI]), and the family APGAR (Adaptability, Partnership, Growth, Affection, Resolve) index. The test results were compared by family relationships, and subgroups were classified based on the donation type: 1) parents to children, 2) grown children to parents, 3) siblings to siblings, 4) spouses to spouses, and 5) other relatives to other relatives. Results: The BDI-II (P < 0.001) and BAI differed considerably according to the donation type in potential donor candidates. Compared with other subgroups, parents donating to their children suffered the most severe psychological stress before LDLT and exhibited more depressive (P < 0.001) and anxiety symptoms. However, the stress associated with grown children donating to their parents, siblings, and spouses was not significantly higher than it was for other relatives. Furthermore, a significant negative correlation existed between family APGAR scores and the severity of depression and anxiety (P < 0.001) among potential donor candidates. Conclusion: These results indicate the importance of understanding potential donor candidates’ psychological characteristics before LT. Greater anxiety and depression may be exhibited by parent donors due to the distress from fears of death or illness of the recipients, or their guilty feeling for their child. Additionally, family dysfunction also revealed more depression and anxiety. Such donor candidates should be given more extensive pre-donation counseling for minimizing pre-LDLT psychological stress. Keywords: living donor candidates, psychosocial evaluation, depression, anxiety, family function, family relationship |
| format |
article |
| author |
Wu MK Hsu LW Huang KT Lin CC Wang CC Lin TL Li WF Goto S Chen CL Chen CC |
| author_facet |
Wu MK Hsu LW Huang KT Lin CC Wang CC Lin TL Li WF Goto S Chen CL Chen CC |
| author_sort |
Wu MK |
| title |
Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| title_short |
Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| title_full |
Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| title_fullStr |
Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| title_full_unstemmed |
Assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| title_sort |
assessment of relevant factors with respect to psychosocial properties in potential living donor candidates before liver transplantation |
| publisher |
Dove Medical Press |
| publishDate |
2018 |
| url |
https://doaj.org/article/a6e2ed92cfdd452e80c2c4e272501490 |
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