Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions

Abstract RNA silencing is an evolutionarily homology-based gene inactivation mechanism and plays critical roles in plant immune responses to acute or chronic virus infections, which often pose serious threats to agricultural productions. Plant antiviral immunity is triggered by virus-derived small i...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Muhammad Dilshad Hussain, Tahir Farooq, Xi Chen, Muhammad Tariqjaveed, Tong Jiang, Sijia Liu, Tao Zhou
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Closterovirids Antiviral RNA silencing Viral pathogenicity Plant immunity Crop disease Plant culture SB1-1110
Acceso en línea:	https://doaj.org/article/a6eeed585ea64669aa96953be08c805e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a6eeed585ea64669aa96953be08c805e
record_format	dspace
spelling	oai:doaj.org-article:a6eeed585ea64669aa96953be08c805e2021-11-21T12:42:13ZViral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions10.1186/s42483-021-00104-y2524-4167https://doaj.org/article/a6eeed585ea64669aa96953be08c805e2021-11-01T00:00:00Zhttps://doi.org/10.1186/s42483-021-00104-yhttps://doaj.org/toc/2524-4167Abstract RNA silencing is an evolutionarily homology-based gene inactivation mechanism and plays critical roles in plant immune responses to acute or chronic virus infections, which often pose serious threats to agricultural productions. Plant antiviral immunity is triggered by virus-derived small interfering RNAs (vsiRNAs) and functions to suppress virus further replication via a sequence-specific degradation manner. Through plant-virus arms races, many viruses have evolved specific protein(s), known as viral suppressors of RNA silencing (VSRs), to combat plant antiviral responses. Numerous reports have shown that VSRs can efficiently curb plant antiviral defense response via interaction with specific component(s) involved in the plant RNA silencing machinery. Members in the family Closteroviridae (closterovirids) are also known to encode VSRs to ensure their infections in plants. In this review, we will focus on the plant antiviral RNA silencing strategies, and the most recent developments on the multifunctional VSRs encoded by closterovirids. Additionally, we will highlight the molecular characters of phylogenetically-associated closterovirids, the interactions of these viruses with their host plants and transmission vectors, and epidemiology.Muhammad Dilshad HussainTahir FarooqXi ChenMuhammad TariqjaveedTong JiangSijia LiuTao ZhouBMCarticleClosteroviridsAntiviral RNA silencingViral pathogenicityPlant immunityCrop diseasePlant cultureSB1-1110ENPhytopathology Research, Vol 3, Iss 1, Pp 1-36 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Closterovirids Antiviral RNA silencing Viral pathogenicity Plant immunity Crop disease Plant culture SB1-1110
spellingShingle	Closterovirids Antiviral RNA silencing Viral pathogenicity Plant immunity Crop disease Plant culture SB1-1110 Muhammad Dilshad Hussain Tahir Farooq Xi Chen Muhammad Tariqjaveed Tong Jiang Sijia Liu Tao Zhou Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions
description	Abstract RNA silencing is an evolutionarily homology-based gene inactivation mechanism and plays critical roles in plant immune responses to acute or chronic virus infections, which often pose serious threats to agricultural productions. Plant antiviral immunity is triggered by virus-derived small interfering RNAs (vsiRNAs) and functions to suppress virus further replication via a sequence-specific degradation manner. Through plant-virus arms races, many viruses have evolved specific protein(s), known as viral suppressors of RNA silencing (VSRs), to combat plant antiviral responses. Numerous reports have shown that VSRs can efficiently curb plant antiviral defense response via interaction with specific component(s) involved in the plant RNA silencing machinery. Members in the family Closteroviridae (closterovirids) are also known to encode VSRs to ensure their infections in plants. In this review, we will focus on the plant antiviral RNA silencing strategies, and the most recent developments on the multifunctional VSRs encoded by closterovirids. Additionally, we will highlight the molecular characters of phylogenetically-associated closterovirids, the interactions of these viruses with their host plants and transmission vectors, and epidemiology.
format	article
author	Muhammad Dilshad Hussain Tahir Farooq Xi Chen Muhammad Tariqjaveed Tong Jiang Sijia Liu Tao Zhou
author_facet	Muhammad Dilshad Hussain Tahir Farooq Xi Chen Muhammad Tariqjaveed Tong Jiang Sijia Liu Tao Zhou
author_sort	Muhammad Dilshad Hussain
title	Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions
title_short	Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions
title_full	Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions
title_fullStr	Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions
title_full_unstemmed	Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions
title_sort	viral suppressors from members of the family closteroviridae combating antiviral rna silencing: a tale of a sophisticated arms race in host-pathogen interactions
publisher	BMC
publishDate	2021
url	https://doaj.org/article/a6eeed585ea64669aa96953be08c805e
work_keys_str_mv	AT muhammaddilshadhussain viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions AT tahirfarooq viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions AT xichen viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions AT muhammadtariqjaveed viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions AT tongjiang viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions AT sijialiu viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions AT taozhou viralsuppressorsfrommembersofthefamilyclosteroviridaecombatingantiviralrnasilencingataleofasophisticatedarmsraceinhostpathogeninteractions
_version_	1718418844547022848

Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions

Ejemplares similares