Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions

Abstract Pyruvate functions as a key molecule in energy production and as an antioxidant. The efficacy of pyruvate supplementation in diabetic retinopathy and nephropathy has been shown in animal models; however, its significance in the functional maintenance of neurons and Schwann cells under diabe...

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Autores principales: Hideji Yako, Naoko Niimi, Ayako Kato, Shizuka Takaku, Yasuaki Tatsumi, Yasumasa Nishito, Koichi Kato, Kazunori Sango
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a6f9d58fa8e244a9b2cbca3a21ee51ce
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