Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling

Kazuyuki Kumagai,1 Nobuchika Ogino,2 Mariko Furukawa,1 Rieko Ooya,1 Eiji Horie3 1Kamiiida Daiichi General Hospital, Nagoya, Japan; 2Nishigaki Eye Clinic, Nagoya, Japan; 3Yata Eye Clinic, Izunokuni, Japan Purpose: The aim of this study was to determine whether the centripetal displacement of the ca...

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Autores principales:	Kumagai K, Ogino N, Furukawa M, Ooya R, Horie E
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	epiretinal membrane foveal avascular zone internal limiting membrane macular hole optical coherence tomography angiography Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/a701418d418b459b96e63a2bc38a1665
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spelling	oai:doaj.org-article:a701418d418b459b96e63a2bc38a16652021-12-02T09:23:47ZEarly centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling1177-5483https://doaj.org/article/a701418d418b459b96e63a2bc38a16652018-04-01T00:00:00Zhttps://www.dovepress.com/early-centripetal-displacements-of-capillaries-in-macular-region-cause-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Kazuyuki Kumagai,1 Nobuchika Ogino,2 Mariko Furukawa,1 Rieko Ooya,1 Eiji Horie3 1Kamiiida Daiichi General Hospital, Nagoya, Japan; 2Nishigaki Eye Clinic, Nagoya, Japan; 3Yata Eye Clinic, Izunokuni, Japan Purpose: The aim of this study was to determine whether the centripetal displacement of the capillaries in the macular region after vitrectomy is caused by internal limiting membrane (ILM) peeling. Methods: Eighteen patients with different types of retinal diseases but with a normal or approximately normal foveal contour underwent successful vitrectomy with (n=12) or without (n=6) ILM peeling. Optical coherence tomography angiography (OCTA) images of the inner retinal vascular plexus in the macular region were analyzed pre- and postoperatively. Four concentric polygonal areas were marked in the OCTA images with the corners selected to be easily identified by vessel bifurcations. The areas of the postoperative foveal avascular zone (FAZ) and the four polygonal regions at about 1 month postoperatively were compared to the baseline areas. Results: Vitrectomy was performed for eleven eyes with vitreomacular tractions, three with macular-on retinal detachments, and four with thin epiretinal membranes. A significant decrease in the FAZ area was observed postoperatively in only the ILM-peeled eyes (P=0.0002). The four polygonal areas in the ILM-peeled eyes decreased after surgery, and the decrease was fit by a linear regression line (R2=0.985–0.999; n=7). The time course of the postoperative decrease of the FAZ area was fit by a hyperbolic curve (R2=0.969–0.998; n=6). The average postoperative time required to reach one-half of the final FAZ area was 1.16 days (0.81–1.62 days). Conclusion: These findings suggest that ILM peeling causes an early centripetal displacement of the capillaries in the macular region. Keywords: epiretinal membrane, foveal avascular zone, internal limiting membrane, macular hole, optical coherence tomography angiographyKumagai KOgino NFurukawa MOoya RHorie EDove Medical Pressarticleepiretinal membranefoveal avascular zoneinternal limiting membranemacular holeoptical coherence tomography angiographyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 755-763 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	epiretinal membrane foveal avascular zone internal limiting membrane macular hole optical coherence tomography angiography Ophthalmology RE1-994
spellingShingle	epiretinal membrane foveal avascular zone internal limiting membrane macular hole optical coherence tomography angiography Ophthalmology RE1-994 Kumagai K Ogino N Furukawa M Ooya R Horie E Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
description	Kazuyuki Kumagai,1 Nobuchika Ogino,2 Mariko Furukawa,1 Rieko Ooya,1 Eiji Horie3 1Kamiiida Daiichi General Hospital, Nagoya, Japan; 2Nishigaki Eye Clinic, Nagoya, Japan; 3Yata Eye Clinic, Izunokuni, Japan Purpose: The aim of this study was to determine whether the centripetal displacement of the capillaries in the macular region after vitrectomy is caused by internal limiting membrane (ILM) peeling. Methods: Eighteen patients with different types of retinal diseases but with a normal or approximately normal foveal contour underwent successful vitrectomy with (n=12) or without (n=6) ILM peeling. Optical coherence tomography angiography (OCTA) images of the inner retinal vascular plexus in the macular region were analyzed pre- and postoperatively. Four concentric polygonal areas were marked in the OCTA images with the corners selected to be easily identified by vessel bifurcations. The areas of the postoperative foveal avascular zone (FAZ) and the four polygonal regions at about 1 month postoperatively were compared to the baseline areas. Results: Vitrectomy was performed for eleven eyes with vitreomacular tractions, three with macular-on retinal detachments, and four with thin epiretinal membranes. A significant decrease in the FAZ area was observed postoperatively in only the ILM-peeled eyes (P=0.0002). The four polygonal areas in the ILM-peeled eyes decreased after surgery, and the decrease was fit by a linear regression line (R2=0.985–0.999; n=7). The time course of the postoperative decrease of the FAZ area was fit by a hyperbolic curve (R2=0.969–0.998; n=6). The average postoperative time required to reach one-half of the final FAZ area was 1.16 days (0.81–1.62 days). Conclusion: These findings suggest that ILM peeling causes an early centripetal displacement of the capillaries in the macular region. Keywords: epiretinal membrane, foveal avascular zone, internal limiting membrane, macular hole, optical coherence tomography angiography
format	article
author	Kumagai K Ogino N Furukawa M Ooya R Horie E
author_facet	Kumagai K Ogino N Furukawa M Ooya R Horie E
author_sort	Kumagai K
title	Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
title_short	Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
title_full	Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
title_fullStr	Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
title_full_unstemmed	Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
title_sort	early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/a701418d418b459b96e63a2bc38a1665
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_version_	1718398139611742208

Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling

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