Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate

In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental ass...

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Autores principales: Katarína Valachová, Ladislav Šoltés
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/a704f5c725e442f1b192f71afd343d17
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spelling oai:doaj.org-article:a704f5c725e442f1b192f71afd343d172021-11-25T18:40:53ZAssessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate10.3390/pharmaceutics131118151999-4923https://doaj.org/article/a704f5c725e442f1b192f71afd343d172021-10-01T00:00:00Zhttps://www.mdpi.com/1999-4923/13/11/1815https://doaj.org/toc/1999-4923In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances.Katarína ValachováLadislav ŠoltésMDPI AGarticlepreventive antioxidantschain-breaking antioxidantsreactive oxygen speciesPharmacy and materia medicaRS1-441ENPharmaceutics, Vol 13, Iss 1815, p 1815 (2021)
institution DOAJ
collection DOAJ
language EN
topic preventive antioxidants
chain-breaking antioxidants
reactive oxygen species
Pharmacy and materia medica
RS1-441
spellingShingle preventive antioxidants
chain-breaking antioxidants
reactive oxygen species
Pharmacy and materia medica
RS1-441
Katarína Valachová
Ladislav Šoltés
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
description In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances.
format article
author Katarína Valachová
Ladislav Šoltés
author_facet Katarína Valachová
Ladislav Šoltés
author_sort Katarína Valachová
title Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_short Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_full Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_fullStr Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_full_unstemmed Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_sort assessment of the substance antioxidative profile by hyaluronan, cu(ii) and ascorbate
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/a704f5c725e442f1b192f71afd343d17
work_keys_str_mv AT katarinavalachova assessmentofthesubstanceantioxidativeprofilebyhyaluronancuiiandascorbate
AT ladislavsoltes assessmentofthesubstanceantioxidativeprofilebyhyaluronancuiiandascorbate
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