Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental ass...
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2021
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oai:doaj.org-article:a704f5c725e442f1b192f71afd343d172021-11-25T18:40:53ZAssessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate10.3390/pharmaceutics131118151999-4923https://doaj.org/article/a704f5c725e442f1b192f71afd343d172021-10-01T00:00:00Zhttps://www.mdpi.com/1999-4923/13/11/1815https://doaj.org/toc/1999-4923In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances.Katarína ValachováLadislav ŠoltésMDPI AGarticlepreventive antioxidantschain-breaking antioxidantsreactive oxygen speciesPharmacy and materia medicaRS1-441ENPharmaceutics, Vol 13, Iss 1815, p 1815 (2021) |
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preventive antioxidants chain-breaking antioxidants reactive oxygen species Pharmacy and materia medica RS1-441 |
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preventive antioxidants chain-breaking antioxidants reactive oxygen species Pharmacy and materia medica RS1-441 Katarína Valachová Ladislav Šoltés Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate |
description |
In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances. |
format |
article |
author |
Katarína Valachová Ladislav Šoltés |
author_facet |
Katarína Valachová Ladislav Šoltés |
author_sort |
Katarína Valachová |
title |
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate |
title_short |
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate |
title_full |
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate |
title_fullStr |
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate |
title_full_unstemmed |
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate |
title_sort |
assessment of the substance antioxidative profile by hyaluronan, cu(ii) and ascorbate |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/a704f5c725e442f1b192f71afd343d17 |
work_keys_str_mv |
AT katarinavalachova assessmentofthesubstanceantioxidativeprofilebyhyaluronancuiiandascorbate AT ladislavsoltes assessmentofthesubstanceantioxidativeprofilebyhyaluronancuiiandascorbate |
_version_ |
1718410854636978176 |