A RNA producing DNA hydrogel as a platform for a high performance RNA interference system

Interfering RNA have a range of therapeutic and research based applications, issues with delivery have made systems that make siRNA in situ of interest. Here, the author report on the creation of a DNA hydrogel with improved stability and transcription efficiency over plasmid DNA.

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Autores principales: Jaejung Song, Minhyuk Lee, Taeyoung Kim, Jeongkyeong Na, Yebin Jung, Gyoo Yeol Jung, Sungjee Kim, Nokyoung Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a70b1bfd43ec42caa1dab8e2a2d576ec
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spelling oai:doaj.org-article:a70b1bfd43ec42caa1dab8e2a2d576ec2021-12-02T14:38:53ZA RNA producing DNA hydrogel as a platform for a high performance RNA interference system10.1038/s41467-018-06864-02041-1723https://doaj.org/article/a70b1bfd43ec42caa1dab8e2a2d576ec2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06864-0https://doaj.org/toc/2041-1723Interfering RNA have a range of therapeutic and research based applications, issues with delivery have made systems that make siRNA in situ of interest. Here, the author report on the creation of a DNA hydrogel with improved stability and transcription efficiency over plasmid DNA.Jaejung SongMinhyuk LeeTaeyoung KimJeongkyeong NaYebin JungGyoo Yeol JungSungjee KimNokyoung ParkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jaejung Song
Minhyuk Lee
Taeyoung Kim
Jeongkyeong Na
Yebin Jung
Gyoo Yeol Jung
Sungjee Kim
Nokyoung Park
A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
description Interfering RNA have a range of therapeutic and research based applications, issues with delivery have made systems that make siRNA in situ of interest. Here, the author report on the creation of a DNA hydrogel with improved stability and transcription efficiency over plasmid DNA.
format article
author Jaejung Song
Minhyuk Lee
Taeyoung Kim
Jeongkyeong Na
Yebin Jung
Gyoo Yeol Jung
Sungjee Kim
Nokyoung Park
author_facet Jaejung Song
Minhyuk Lee
Taeyoung Kim
Jeongkyeong Na
Yebin Jung
Gyoo Yeol Jung
Sungjee Kim
Nokyoung Park
author_sort Jaejung Song
title A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
title_short A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
title_full A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
title_fullStr A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
title_full_unstemmed A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
title_sort rna producing dna hydrogel as a platform for a high performance rna interference system
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a70b1bfd43ec42caa1dab8e2a2d576ec
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