A RNA producing DNA hydrogel as a platform for a high performance RNA interference system
Interfering RNA have a range of therapeutic and research based applications, issues with delivery have made systems that make siRNA in situ of interest. Here, the author report on the creation of a DNA hydrogel with improved stability and transcription efficiency over plasmid DNA.
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Nature Portfolio
2018
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oai:doaj.org-article:a70b1bfd43ec42caa1dab8e2a2d576ec2021-12-02T14:38:53ZA RNA producing DNA hydrogel as a platform for a high performance RNA interference system10.1038/s41467-018-06864-02041-1723https://doaj.org/article/a70b1bfd43ec42caa1dab8e2a2d576ec2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06864-0https://doaj.org/toc/2041-1723Interfering RNA have a range of therapeutic and research based applications, issues with delivery have made systems that make siRNA in situ of interest. Here, the author report on the creation of a DNA hydrogel with improved stability and transcription efficiency over plasmid DNA.Jaejung SongMinhyuk LeeTaeyoung KimJeongkyeong NaYebin JungGyoo Yeol JungSungjee KimNokyoung ParkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Jaejung Song Minhyuk Lee Taeyoung Kim Jeongkyeong Na Yebin Jung Gyoo Yeol Jung Sungjee Kim Nokyoung Park A RNA producing DNA hydrogel as a platform for a high performance RNA interference system |
description |
Interfering RNA have a range of therapeutic and research based applications, issues with delivery have made systems that make siRNA in situ of interest. Here, the author report on the creation of a DNA hydrogel with improved stability and transcription efficiency over plasmid DNA. |
format |
article |
author |
Jaejung Song Minhyuk Lee Taeyoung Kim Jeongkyeong Na Yebin Jung Gyoo Yeol Jung Sungjee Kim Nokyoung Park |
author_facet |
Jaejung Song Minhyuk Lee Taeyoung Kim Jeongkyeong Na Yebin Jung Gyoo Yeol Jung Sungjee Kim Nokyoung Park |
author_sort |
Jaejung Song |
title |
A RNA producing DNA hydrogel as a platform for a high performance RNA interference system |
title_short |
A RNA producing DNA hydrogel as a platform for a high performance RNA interference system |
title_full |
A RNA producing DNA hydrogel as a platform for a high performance RNA interference system |
title_fullStr |
A RNA producing DNA hydrogel as a platform for a high performance RNA interference system |
title_full_unstemmed |
A RNA producing DNA hydrogel as a platform for a high performance RNA interference system |
title_sort |
rna producing dna hydrogel as a platform for a high performance rna interference system |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/a70b1bfd43ec42caa1dab8e2a2d576ec |
work_keys_str_mv |
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1718390853930582016 |