Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study

Abstract To explore the impact of high-intensity focused ultrasound (HIFU) ablation of uterine fibroids in nulliparous women on subsequent pregnancy and delivery. A retrospective analysis was conducted of nulliparous women who received HIFU treatment at Chongqing Medical University, Chongqing,China,...

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Autores principales:	Jun shu Li, Yong Wang, Jin yun Chen, Wen zhi Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a71d2fb16c944431b5090cb0365aa26d
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spelling	oai:doaj.org-article:a71d2fb16c944431b5090cb0365aa26d2021-12-02T15:06:11ZPregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study10.1038/s41598-017-04319-y2045-2322https://doaj.org/article/a71d2fb16c944431b5090cb0365aa26d2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04319-yhttps://doaj.org/toc/2045-2322Abstract To explore the impact of high-intensity focused ultrasound (HIFU) ablation of uterine fibroids in nulliparous women on subsequent pregnancy and delivery. A retrospective analysis was conducted of nulliparous women who received HIFU treatment at Chongqing Medical University, Chongqing,China, from January 1, 2010, to January 1, 2015. A total of 189 cases were enrolled, the median follow-up time was three years. Among them,there were 131 cases pregnancy with a total of 133 times,the pregnancy rate was 69.3% (131/189),and the spontaneous conception rate was 95.4% (125/131). Of 131 pregnant women, 19 were on-going pregnancy, terminated pregnancy 114 times,which include 93 times successfully delivery with a 76.3% (87/114) full-term birth rate,and the cesarean section rate was 72.0% (67/93). Of 94 newborns,the average birth weight was (3.3 ± 0.4)kg (range:1.5–4.8 kg), and a pair of them were identical twins. The incidence of complications during pregnancy and delivery were 10.8% (10/93) and 7.5% (7/93),respectively,except one woman failed on-going pregnancy and one woman suffered hysterectomy due to the complications,others all successful pregnant and delivered. Multiple-factor regression analysis found that age and infertility history were the important factors that may affect pregnancy after HIFU (P < 0.01). Nulliparous women who undergo HIFU treatment for uterine fibroids can subsequently have successful pregnancy and delivery safely.Jun shu LiYong WangJin yun ChenWen zhi ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jun shu Li Yong Wang Jin yun Chen Wen zhi Chen Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study
description	Abstract To explore the impact of high-intensity focused ultrasound (HIFU) ablation of uterine fibroids in nulliparous women on subsequent pregnancy and delivery. A retrospective analysis was conducted of nulliparous women who received HIFU treatment at Chongqing Medical University, Chongqing,China, from January 1, 2010, to January 1, 2015. A total of 189 cases were enrolled, the median follow-up time was three years. Among them,there were 131 cases pregnancy with a total of 133 times,the pregnancy rate was 69.3% (131/189),and the spontaneous conception rate was 95.4% (125/131). Of 131 pregnant women, 19 were on-going pregnancy, terminated pregnancy 114 times,which include 93 times successfully delivery with a 76.3% (87/114) full-term birth rate,and the cesarean section rate was 72.0% (67/93). Of 94 newborns,the average birth weight was (3.3 ± 0.4)kg (range:1.5–4.8 kg), and a pair of them were identical twins. The incidence of complications during pregnancy and delivery were 10.8% (10/93) and 7.5% (7/93),respectively,except one woman failed on-going pregnancy and one woman suffered hysterectomy due to the complications,others all successful pregnant and delivered. Multiple-factor regression analysis found that age and infertility history were the important factors that may affect pregnancy after HIFU (P < 0.01). Nulliparous women who undergo HIFU treatment for uterine fibroids can subsequently have successful pregnancy and delivery safely.
format	article
author	Jun shu Li Yong Wang Jin yun Chen Wen zhi Chen
author_facet	Jun shu Li Yong Wang Jin yun Chen Wen zhi Chen
author_sort	Jun shu Li
title	Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study
title_short	Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study
title_full	Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study
title_fullStr	Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study
title_full_unstemmed	Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study
title_sort	pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: a single-central retrospective study
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a71d2fb16c944431b5090cb0365aa26d
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Pregnancy outcomes in nulliparous women after ultrasound ablation of uterine fibroids: A single-central retrospective study

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