Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study

Objective: To assess the procalcitonin protocol use and its impact on antibiotic therapy management of critically ill patients in the intensive care unit (ICU). Method: An observational descriptive and retrospective study conducted in an adult ICU with 28 beds from the Brazilian Unified Health Syst...

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Autores principales:	Danillo E. OLIVEIRA, Eudes G. CUNHA, Diana M. GUERRA, Valéria S. BEZERRA
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2021
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/a722924ec6884ae9834be923d394c9d3
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spelling	oai:doaj.org-article:a722924ec6884ae9834be923d394c9d32021-11-28T02:42:51ZProcalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study10.30968/rbfhss.2021.122.05632179-59242316-7750https://doaj.org/article/a722924ec6884ae9834be923d394c9d32021-06-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/563https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Objective: To assess the procalcitonin protocol use and its impact on antibiotic therapy management of critically ill patients in the intensive care unit (ICU). Method: An observational descriptive and retrospective study conducted in an adult ICU with 28 beds from the Brazilian Unified Health System (SUS). Results: This present study observed a 78% (90/116) of PCT protocol adherence in the studied ICU. We observed a reduction in days of antibiotic treatment (DOT) going from 14 to 8,5 treatment-day duration (5.49 ± 2.2 days), impacting the overall antibiotic therapy cost for a decrease of 40.91%. Conclusion: The study revealed that PCT use was associated with substantial benefits, reducing hospital costs and days of exposure to antibiotic therapy applied to patients affected by infectious diseases in critical care settings. Danillo E. OLIVEIRAEudes G. CUNHADiana M. GUERRAValéria S. BEZERRASociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Danillo E. OLIVEIRA Eudes G. CUNHA Diana M. GUERRA Valéria S. BEZERRA Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
description	Objective: To assess the procalcitonin protocol use and its impact on antibiotic therapy management of critically ill patients in the intensive care unit (ICU). Method: An observational descriptive and retrospective study conducted in an adult ICU with 28 beds from the Brazilian Unified Health System (SUS). Results: This present study observed a 78% (90/116) of PCT protocol adherence in the studied ICU. We observed a reduction in days of antibiotic treatment (DOT) going from 14 to 8,5 treatment-day duration (5.49 ± 2.2 days), impacting the overall antibiotic therapy cost for a decrease of 40.91%. Conclusion: The study revealed that PCT use was associated with substantial benefits, reducing hospital costs and days of exposure to antibiotic therapy applied to patients affected by infectious diseases in critical care settings.
format	article
author	Danillo E. OLIVEIRA Eudes G. CUNHA Diana M. GUERRA Valéria S. BEZERRA
author_facet	Danillo E. OLIVEIRA Eudes G. CUNHA Diana M. GUERRA Valéria S. BEZERRA
author_sort	Danillo E. OLIVEIRA
title	Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
title_short	Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
title_full	Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
title_fullStr	Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
title_full_unstemmed	Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
title_sort	procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2021
url	https://doaj.org/article/a722924ec6884ae9834be923d394c9d3
work_keys_str_mv	AT danilloeoliveira procalcitoninguidedprotocoluseandimpactonintensivecareunitandantibioticmanagementapilotstudy AT eudesgcunha procalcitoninguidedprotocoluseandimpactonintensivecareunitandantibioticmanagementapilotstudy AT dianamguerra procalcitoninguidedprotocoluseandimpactonintensivecareunitandantibioticmanagementapilotstudy AT valeriasbezerra procalcitoninguidedprotocoluseandimpactonintensivecareunitandantibioticmanagementapilotstudy
_version_	1718408457807200256

Procalcitonin-guided protocol use and impact on intensive care unit and antibiotic management: a pilot study

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