A Validation Method for EPID In Vivo Dosimetry Algorithms

The aim of this study was to develop and apply an evaluation method for assessing the accuracy of a novel 3D EPID back-projection algorithm for in vivo dosimetry. The novel algorithm of Dosimetry Check (DC) 5.8 was evaluated. A slab phantom homogeneously filled, or with air and bone inserts, was use...

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Autores principales:	Marco Esposito, Livia Marrazzo, Eleonora Vanzi, Serenella Russo, Stefania Pallotta, Cinzia Talamonti
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	in vivo dosimetry EPID end-to-end test anthropomorphic phantom Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/a72670be21734895998a2df0978e1ed9
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id	oai:doaj.org-article:a72670be21734895998a2df0978e1ed9
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spelling	oai:doaj.org-article:a72670be21734895998a2df0978e1ed92021-11-25T16:36:11ZA Validation Method for EPID In Vivo Dosimetry Algorithms10.3390/app1122107152076-3417https://doaj.org/article/a72670be21734895998a2df0978e1ed92021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/10715https://doaj.org/toc/2076-3417The aim of this study was to develop and apply an evaluation method for assessing the accuracy of a novel 3D EPID back-projection algorithm for in vivo dosimetry. The novel algorithm of Dosimetry Check (DC) 5.8 was evaluated. A slab phantom homogeneously filled, or with air and bone inserts, was used for fluence reconstruction of different squared fields. VMAT plans in different anatomical sites were delivered on an anthropomorphic phantom. Dose distributions were measured with radiochromic films. The 2D Gamma Agreement Index (GAI) between the DC and the film dose distributions (3%, 3 mm) was computed for assessing the accuracy of the algorithm. GAIs between films and TPS and between DC and TPS were also computed. The fluence reconstruction accuracy was within 2% for all squared fields in the three slabs’ configurations. The GAI between the DC and the film was 92.7% in the prostate, 92.9% in the lung, 96.6% in the head and the neck, and 94.6% in the brain. An evaluation method for assessing the accuracy of a novel EPID algorithm was developed. The DC algorithm was shown to be able to accurately reconstruct doses in all anatomic sites, including the lung. The methodology described in the present study can be applied to any EPID back-projection in vivo algorithm.Marco EspositoLivia MarrazzoEleonora VanziSerenella RussoStefania PallottaCinzia TalamontiMDPI AGarticlein vivo dosimetryEPIDend-to-end testanthropomorphic phantomTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10715, p 10715 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	in vivo dosimetry EPID end-to-end test anthropomorphic phantom Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
spellingShingle	in vivo dosimetry EPID end-to-end test anthropomorphic phantom Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 Marco Esposito Livia Marrazzo Eleonora Vanzi Serenella Russo Stefania Pallotta Cinzia Talamonti A Validation Method for EPID In Vivo Dosimetry Algorithms
description	The aim of this study was to develop and apply an evaluation method for assessing the accuracy of a novel 3D EPID back-projection algorithm for in vivo dosimetry. The novel algorithm of Dosimetry Check (DC) 5.8 was evaluated. A slab phantom homogeneously filled, or with air and bone inserts, was used for fluence reconstruction of different squared fields. VMAT plans in different anatomical sites were delivered on an anthropomorphic phantom. Dose distributions were measured with radiochromic films. The 2D Gamma Agreement Index (GAI) between the DC and the film dose distributions (3%, 3 mm) was computed for assessing the accuracy of the algorithm. GAIs between films and TPS and between DC and TPS were also computed. The fluence reconstruction accuracy was within 2% for all squared fields in the three slabs’ configurations. The GAI between the DC and the film was 92.7% in the prostate, 92.9% in the lung, 96.6% in the head and the neck, and 94.6% in the brain. An evaluation method for assessing the accuracy of a novel EPID algorithm was developed. The DC algorithm was shown to be able to accurately reconstruct doses in all anatomic sites, including the lung. The methodology described in the present study can be applied to any EPID back-projection in vivo algorithm.
format	article
author	Marco Esposito Livia Marrazzo Eleonora Vanzi Serenella Russo Stefania Pallotta Cinzia Talamonti
author_facet	Marco Esposito Livia Marrazzo Eleonora Vanzi Serenella Russo Stefania Pallotta Cinzia Talamonti
author_sort	Marco Esposito
title	A Validation Method for EPID In Vivo Dosimetry Algorithms
title_short	A Validation Method for EPID In Vivo Dosimetry Algorithms
title_full	A Validation Method for EPID In Vivo Dosimetry Algorithms
title_fullStr	A Validation Method for EPID In Vivo Dosimetry Algorithms
title_full_unstemmed	A Validation Method for EPID In Vivo Dosimetry Algorithms
title_sort	validation method for epid in vivo dosimetry algorithms
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a72670be21734895998a2df0978e1ed9
work_keys_str_mv	AT marcoesposito avalidationmethodforepidinvivodosimetryalgorithms AT liviamarrazzo avalidationmethodforepidinvivodosimetryalgorithms AT eleonoravanzi avalidationmethodforepidinvivodosimetryalgorithms AT serenellarusso avalidationmethodforepidinvivodosimetryalgorithms AT stefaniapallotta avalidationmethodforepidinvivodosimetryalgorithms AT cinziatalamonti avalidationmethodforepidinvivodosimetryalgorithms AT marcoesposito validationmethodforepidinvivodosimetryalgorithms AT liviamarrazzo validationmethodforepidinvivodosimetryalgorithms AT eleonoravanzi validationmethodforepidinvivodosimetryalgorithms AT serenellarusso validationmethodforepidinvivodosimetryalgorithms AT stefaniapallotta validationmethodforepidinvivodosimetryalgorithms AT cinziatalamonti validationmethodforepidinvivodosimetryalgorithms
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A Validation Method for EPID In Vivo Dosimetry Algorithms

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