Topical azithromycin or ofloxacin for endophthalmitis

Topical azithromycin or ofloxacin for endophthalmitis

Michael W Stewart, Michael L StewartDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USAThe recently published study by Romero-Aroca et al1 raises interesting questions regarding the effect of choice of topical antibiotic (azithromycin versus ofloxacin) on the incidence of endophthalmitis...

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Autores principales: Stewart ML, Stewart MW
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2012
Materias:
Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/a72d39a81b354c47b8017ce84a74fa22
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spelling oai:doaj.org-article:a72d39a81b354c47b8017ce84a74fa222021-12-02T01:59:50ZTopical azithromycin or ofloxacin for endophthalmitis1177-54671177-5483https://doaj.org/article/a72d39a81b354c47b8017ce84a74fa222012-12-01T00:00:00Zhttp://www.dovepress.com/topical-azithromycin-or-ofloxacin-for-endophthalmitis-a11844https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Michael W Stewart, Michael L StewartDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USAThe recently published study by Romero-Aroca et al1 raises interesting questions regarding the effect of choice of topical antibiotic (azithromycin versus ofloxacin) on the incidence of endophthalmitis following intravitreal injections. However, important conclusions advanced by the authors deserve further discussion. First, the authors state that use of azithromycin leads to significantly fewer cases of post-injection endophthalmitis than does the use of ofloxacin. Their prospective series shows a lower endophthalmitis rate in eyes treated with azithromycin (two cases in 4045 injections, 0.049%) than in eyes treated with ofloxacin (five cases in 4151 injections, 0.12%). They calculate a relative risk of 2.37, and conclude that this was statistically significant (confidence interval 1.37–3.72; P < 0.001).View original paper by Romero-Aroca and colleagues.Stewart MLStewart MWDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 35-38 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Stewart ML
Stewart MW
Topical azithromycin or ofloxacin for endophthalmitis
description Michael W Stewart, Michael L StewartDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USAThe recently published study by Romero-Aroca et al1 raises interesting questions regarding the effect of choice of topical antibiotic (azithromycin versus ofloxacin) on the incidence of endophthalmitis following intravitreal injections. However, important conclusions advanced by the authors deserve further discussion. First, the authors state that use of azithromycin leads to significantly fewer cases of post-injection endophthalmitis than does the use of ofloxacin. Their prospective series shows a lower endophthalmitis rate in eyes treated with azithromycin (two cases in 4045 injections, 0.049%) than in eyes treated with ofloxacin (five cases in 4151 injections, 0.12%). They calculate a relative risk of 2.37, and conclude that this was statistically significant (confidence interval 1.37–3.72; P < 0.001).View original paper by Romero-Aroca and colleagues.
format article
author Stewart ML
Stewart MW
author_facet Stewart ML
Stewart MW
author_sort Stewart ML
title Topical azithromycin or ofloxacin for endophthalmitis
title_short Topical azithromycin or ofloxacin for endophthalmitis
title_full Topical azithromycin or ofloxacin for endophthalmitis
title_fullStr Topical azithromycin or ofloxacin for endophthalmitis
title_full_unstemmed Topical azithromycin or ofloxacin for endophthalmitis
title_sort topical azithromycin or ofloxacin for endophthalmitis
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/a72d39a81b354c47b8017ce84a74fa22
work_keys_str_mv AT stewartml topicalazithromycinorofloxacinforendophthalmitis
AT stewartmw topicalazithromycinorofloxacinforendophthalmitis
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