DNA hydrolysing IgG catalytic antibodies: an emerging link between psychoses and autoimmunity

Abstract It is not uncommon to observe autoimmune comorbidities in a significant subset of patients with psychotic disorders, namely schizophrenia (SCZ) and bipolar disorder (BPD). To understand the autoimmune basis, the DNA abyzme activity mediated by serum polyclonal IgG Abs were examined in psych...

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Auteurs principaux: Rajendran Ramesh, Aparna Sundaresh, Ravi Philip Rajkumar, Vir Singh Negi, M. A. Vijayalakshmi, Rajagopal Krishnamoorthy, Ryad Tamouza, Marion Leboyer, A. S. Kamalanathan
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/a73844f9cf9e4529849057be02e8e7dd
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