The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.

<h4>Background</h4>Among senior drivers, benzodiazepines (BZDs) have a documented effect on the risk of road traffic crashes (RTCs). It remains unclear however if BZDs play the same role when considering marital status. Therefore, we aimed to investigate the role of marital status in the...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kristina Johnell, Lucie Laflamme, Jette Möller, Joel Monárrez-Espino
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a73863bba47d45aab9c98a69062cf306
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a73863bba47d45aab9c98a69062cf306
record_format	dspace
spelling	oai:doaj.org-article:a73863bba47d45aab9c98a69062cf3062021-11-18T08:35:08ZThe role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.1932-620310.1371/journal.pone.0086742https://doaj.org/article/a73863bba47d45aab9c98a69062cf3062014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24489781/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Among senior drivers, benzodiazepines (BZDs) have a documented effect on the risk of road traffic crashes (RTCs). It remains unclear however if BZDs play the same role when considering marital status. Therefore, we aimed to investigate the role of marital status in the association between BZD use and injurious RTCs among senior drivers.<h4>Methods</h4>Matched case-control study based on five national Swedish registers (n = 154 225). Cases comprised the first non-alcohol-related injurious RTC sustained by drivers aged 50-80 years from July 2005 to December 2009 and controls included registered residents with a valid license who did not crash during that period. Four controls were matched to each case by sex, age and place of residence. Conditional logistic regression analysis for injurious RTC was performed with adjustment for occupation and number of medications. The main exposure was dispensation of BZDs, alone or in combination with other psychotropic medications, 1-30 days prior to the crash date stratified by marital status.<h4>Results</h4>BZD use, alone or in combination with other psychotropic medications, increased the risk of being involved in an RTC (BZD only: adjusted OR: 1.26, 95% CI: 1.17-1.36; BZDs and other psychotropics: adjusted OR: 1.25, 95% CI: 1.12-1.41). Compared to married drivers, those divorced (1.48, 1.43-1.53) and widowed (1.54; 1.45-1.63) had higher adjusted ORs. Marital status modified the association between BZDs and RTCs, particularly among younger male drivers.<h4>Conclusions</h4>Both BZDs and marital status independently affect the risk for senior drivers to be involved in an RTC. However, marital status plays a role in the association between BZD use and RTCs and this may have implications for targeting risk populations for RTCs among senior drivers.Kristina JohnellLucie LaflammeJette MöllerJoel Monárrez-EspinoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e86742 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kristina Johnell Lucie Laflamme Jette Möller Joel Monárrez-Espino The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.
description	<h4>Background</h4>Among senior drivers, benzodiazepines (BZDs) have a documented effect on the risk of road traffic crashes (RTCs). It remains unclear however if BZDs play the same role when considering marital status. Therefore, we aimed to investigate the role of marital status in the association between BZD use and injurious RTCs among senior drivers.<h4>Methods</h4>Matched case-control study based on five national Swedish registers (n = 154 225). Cases comprised the first non-alcohol-related injurious RTC sustained by drivers aged 50-80 years from July 2005 to December 2009 and controls included registered residents with a valid license who did not crash during that period. Four controls were matched to each case by sex, age and place of residence. Conditional logistic regression analysis for injurious RTC was performed with adjustment for occupation and number of medications. The main exposure was dispensation of BZDs, alone or in combination with other psychotropic medications, 1-30 days prior to the crash date stratified by marital status.<h4>Results</h4>BZD use, alone or in combination with other psychotropic medications, increased the risk of being involved in an RTC (BZD only: adjusted OR: 1.26, 95% CI: 1.17-1.36; BZDs and other psychotropics: adjusted OR: 1.25, 95% CI: 1.12-1.41). Compared to married drivers, those divorced (1.48, 1.43-1.53) and widowed (1.54; 1.45-1.63) had higher adjusted ORs. Marital status modified the association between BZDs and RTCs, particularly among younger male drivers.<h4>Conclusions</h4>Both BZDs and marital status independently affect the risk for senior drivers to be involved in an RTC. However, marital status plays a role in the association between BZD use and RTCs and this may have implications for targeting risk populations for RTCs among senior drivers.
format	article
author	Kristina Johnell Lucie Laflamme Jette Möller Joel Monárrez-Espino
author_facet	Kristina Johnell Lucie Laflamme Jette Möller Joel Monárrez-Espino
author_sort	Kristina Johnell
title	The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.
title_short	The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.
title_full	The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.
title_fullStr	The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.
title_full_unstemmed	The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.
title_sort	role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in sweden.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/a73863bba47d45aab9c98a69062cf306
work_keys_str_mv	AT kristinajohnell theroleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT lucielaflamme theroleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT jettemoller theroleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT joelmonarrezespino theroleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT kristinajohnell roleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT lucielaflamme roleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT jettemoller roleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden AT joelmonarrezespino roleofmaritalstatusintheassociationbetweenbenzodiazepinespsychotropicsandinjuriousroadtrafficcrashesaregisterbasednationwidestudyofseniordriversinsweden
_version_	1718421639374307328

The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden.

Ejemplares similares