A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer

Improved therapeutics are needed for treating breast cancer. Here they show the druggability of myoferlin with a small molecule inhibitor in breast cancer and demonstrate its anti-breast cancer effects in vitro and in vivo.

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Auteurs principaux:	Tao Zhang, Jingjie Li, Yuan He, Feifei Yang, Yun Hao, Wangrui Jin, Jing Wu, Zhenliang Sun, Yunqi Li, Yihua Chen, Zhengfang Yi, Mingyao Liu
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/a73b563276a4425294fa01eeae77ed30
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spelling	oai:doaj.org-article:a73b563276a4425294fa01eeae77ed302021-12-02T16:50:10ZA small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer10.1038/s41467-018-06179-02041-1723https://doaj.org/article/a73b563276a4425294fa01eeae77ed302018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06179-0https://doaj.org/toc/2041-1723Improved therapeutics are needed for treating breast cancer. Here they show the druggability of myoferlin with a small molecule inhibitor in breast cancer and demonstrate its anti-breast cancer effects in vitro and in vivo.Tao ZhangJingjie LiYuan HeFeifei YangYun HaoWangrui JinJing WuZhenliang SunYunqi LiYihua ChenZhengfang YiMingyao LiuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tao Zhang Jingjie Li Yuan He Feifei Yang Yun Hao Wangrui Jin Jing Wu Zhenliang Sun Yunqi Li Yihua Chen Zhengfang Yi Mingyao Liu A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
description	Improved therapeutics are needed for treating breast cancer. Here they show the druggability of myoferlin with a small molecule inhibitor in breast cancer and demonstrate its anti-breast cancer effects in vitro and in vivo.
format	article
author	Tao Zhang Jingjie Li Yuan He Feifei Yang Yun Hao Wangrui Jin Jing Wu Zhenliang Sun Yunqi Li Yihua Chen Zhengfang Yi Mingyao Liu
author_facet	Tao Zhang Jingjie Li Yuan He Feifei Yang Yun Hao Wangrui Jin Jing Wu Zhenliang Sun Yunqi Li Yihua Chen Zhengfang Yi Mingyao Liu
author_sort	Tao Zhang
title	A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
title_short	A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
title_full	A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
title_fullStr	A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
title_full_unstemmed	A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
title_sort	small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a73b563276a4425294fa01eeae77ed30
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A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer

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