Single-cell reconstruction of follicular remodeling in the human adult ovary

In the ovary, follicular degeneration occurs after folliculogenesis, with one dominant follicle reaching maturity every month. Here, by performing single cell RNA-seq of adult human follicles, the authors identify subclasses of granulosa and theca cell lineages, which correlate with the growth or de...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	X. Fan, M. Bialecka, I. Moustakas, E. Lam, V. Torrens-Juaneda, N. V. Borggreven, L. Trouw, L. A. Louwe, G. S. K. Pilgram, H. Mei, L. van der Westerlaken, S. M. Chuva de Sousa Lopes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a7401d07ed204ad8a215860ccf7392d9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a7401d07ed204ad8a215860ccf7392d9
record_format	dspace
spelling	oai:doaj.org-article:a7401d07ed204ad8a215860ccf7392d92021-12-02T14:39:19ZSingle-cell reconstruction of follicular remodeling in the human adult ovary10.1038/s41467-019-11036-92041-1723https://doaj.org/article/a7401d07ed204ad8a215860ccf7392d92019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11036-9https://doaj.org/toc/2041-1723In the ovary, follicular degeneration occurs after folliculogenesis, with one dominant follicle reaching maturity every month. Here, by performing single cell RNA-seq of adult human follicles, the authors identify subclasses of granulosa and theca cell lineages, which correlate with the growth or degeneration of the follicles.X. FanM. BialeckaI. MoustakasE. LamV. Torrens-JuanedaN. V. BorggrevenL. TrouwL. A. LouweG. S. K. PilgramH. MeiL. van der WesterlakenS. M. Chuva de Sousa LopesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q X. Fan M. Bialecka I. Moustakas E. Lam V. Torrens-Juaneda N. V. Borggreven L. Trouw L. A. Louwe G. S. K. Pilgram H. Mei L. van der Westerlaken S. M. Chuva de Sousa Lopes Single-cell reconstruction of follicular remodeling in the human adult ovary
description	In the ovary, follicular degeneration occurs after folliculogenesis, with one dominant follicle reaching maturity every month. Here, by performing single cell RNA-seq of adult human follicles, the authors identify subclasses of granulosa and theca cell lineages, which correlate with the growth or degeneration of the follicles.
format	article
author	X. Fan M. Bialecka I. Moustakas E. Lam V. Torrens-Juaneda N. V. Borggreven L. Trouw L. A. Louwe G. S. K. Pilgram H. Mei L. van der Westerlaken S. M. Chuva de Sousa Lopes
author_facet	X. Fan M. Bialecka I. Moustakas E. Lam V. Torrens-Juaneda N. V. Borggreven L. Trouw L. A. Louwe G. S. K. Pilgram H. Mei L. van der Westerlaken S. M. Chuva de Sousa Lopes
author_sort	X. Fan
title	Single-cell reconstruction of follicular remodeling in the human adult ovary
title_short	Single-cell reconstruction of follicular remodeling in the human adult ovary
title_full	Single-cell reconstruction of follicular remodeling in the human adult ovary
title_fullStr	Single-cell reconstruction of follicular remodeling in the human adult ovary
title_full_unstemmed	Single-cell reconstruction of follicular remodeling in the human adult ovary
title_sort	single-cell reconstruction of follicular remodeling in the human adult ovary
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a7401d07ed204ad8a215860ccf7392d9
work_keys_str_mv	AT xfan singlecellreconstructionoffollicularremodelinginthehumanadultovary AT mbialecka singlecellreconstructionoffollicularremodelinginthehumanadultovary AT imoustakas singlecellreconstructionoffollicularremodelinginthehumanadultovary AT elam singlecellreconstructionoffollicularremodelinginthehumanadultovary AT vtorrensjuaneda singlecellreconstructionoffollicularremodelinginthehumanadultovary AT nvborggreven singlecellreconstructionoffollicularremodelinginthehumanadultovary AT ltrouw singlecellreconstructionoffollicularremodelinginthehumanadultovary AT lalouwe singlecellreconstructionoffollicularremodelinginthehumanadultovary AT gskpilgram singlecellreconstructionoffollicularremodelinginthehumanadultovary AT hmei singlecellreconstructionoffollicularremodelinginthehumanadultovary AT lvanderwesterlaken singlecellreconstructionoffollicularremodelinginthehumanadultovary AT smchuvadesousalopes singlecellreconstructionoffollicularremodelinginthehumanadultovary
_version_	1718390674790809600

Single-cell reconstruction of follicular remodeling in the human adult ovary

Ejemplares similares