Single-cell reconstruction of follicular remodeling in the human adult ovary

In the ovary, follicular degeneration occurs after folliculogenesis, with one dominant follicle reaching maturity every month. Here, by performing single cell RNA-seq of adult human follicles, the authors identify subclasses of granulosa and theca cell lineages, which correlate with the growth or de...

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Bibliographic Details
Main Authors: X. Fan, M. Bialecka, I. Moustakas, E. Lam, V. Torrens-Juaneda, N. V. Borggreven, L. Trouw, L. A. Louwe, G. S. K. Pilgram, H. Mei, L. van der Westerlaken, S. M. Chuva de Sousa Lopes
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/a7401d07ed204ad8a215860ccf7392d9
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