Isocyanide Substitution in Acridine Orange Shifts DNA Damage-Mediated Phototoxicity to Permeabilization of the Lysosomal Membrane in Cancer Cells

In cancer therapy, immunogenic cell death eliminates tumor cells more efficiently than conventional apoptosis. During photodynamic therapy (PDT), some photosensitizer (PS) targeting lysosomes divert apoptosis to the immunologically more relevant necrosis-like cell death. Acridine orange (AO) is a PS...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Csaba Bankó, Zsolt László Nagy, Miklós Nagy, Gábor György Szemán-Nagy, István Rebenku, László Imre, Attila Tiba, András Hajdu, János Szöllősi, Sándor Kéki, Zsolt Bacso
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
Accès en ligne:https://doaj.org/article/a74b4d986bc54330807323d3b2bc6a4a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!